{"id":"W3108108082","doi":"10.1016/j.plefa.2020.102220","title":"Prostaglandins as potential targets for the treatment of polycystic kidney disease","year":2020,"lang":"en","type":"review","venue":"Prostaglandins Leukotrienes and Essential Fatty Acids","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Polycystic kidney disease; Kidney; Nephrotoxicity; Endocrinology; Internal medicine; Kidney disease; Cyclic adenosine monophosphate; Medicine; Cyclooxygenase; Pharmacology; Biology; Receptor; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006851165,0.0007810266,0.001767526,0.001745891,0.000213942,0.001024645,0.0008114483,0.001117604,0.003988539],"category_scores_gemma":[0.0007773745,0.0002118005,0.0004058499,0.00157549,0.0004432189,0.001051395,0.0006497719,0.00269223,0.002031045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005754593,"about_ca_system_score_gemma":0.001008011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009169372,"about_ca_topic_score_gemma":0.001848233,"domain_scores_codex":[0.9998357,0.00003226344,0.00002121282,0.0000221213,0.00006828092,0.00002038384],"domain_scores_gemma":[0.9997063,0.0001382625,0.0000414135,0.000007477445,0.00006770017,0.00003872352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002808845,0.00009585585,0.0001386581,0.01379364,0.0001345291,0.0002960604,0.00004255335,0.0004522986,0.002506204,0.005271017,0.04417565,0.9328127],"study_design_scores_gemma":[0.0001130841,0.0001782119,0.0007154931,0.003404426,0.0002168974,0.001179913,0.00005819301,0.0001396303,0.0005573488,0.003165588,0.9902469,0.00002432074],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005869638,0.9989994,0.00007873598,0.0002221311,0.0002239918,0.000002678562,0.00001560851,0.000005236748,0.0003935996],"genre_scores_gemma":[0.0004395259,0.998603,0.0001280618,0.0001876916,0.0002191859,0.000004531967,0.00002873339,0.000001037343,0.000388202],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003988539,"threshold_uncertainty_score":0.01334298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527641009187741,"score_gpt":0.2890243119779474,"score_spread":0.27374790188607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}