{"id":"W3108249746","doi":"10.1002/ijc.33416","title":"Circulating insulin‐like growth factor‐I, total and free testosterone concentrations and prostate cancer risk in 200 000 men in UK Biobank","year":2020,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Medical Research Council; Medical Research Council Canada; National Institute for Health and Care Research; Wellcome Trust; British Heart Foundation; National Cancer Institute; Cancer Research UK; World Health Organization","keywords":"Prostate cancer; Medicine; Hazard ratio; Prospective cohort study; Internal medicine; Sex hormone-binding globulin; Testosterone (patch); Cancer; Risk factor; Odds ratio; Proportional hazards model; Insulin-like growth factor; Oncology; Prostate; Gynecology; Endocrinology; Hormone; Androgen; Confidence interval; Growth factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001125646,0.000116035,0.0002369479,0.0001682986,0.00002787791,0.00004888561,0.00009734694,0.00004745267,0.000143577],"category_scores_gemma":[0.0001464315,0.00009184166,0.00003323338,0.0001584706,0.00008280781,0.0002116649,0.00006087608,0.0003397684,5.277595e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003546329,"about_ca_system_score_gemma":0.0003171451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001923886,"about_ca_topic_score_gemma":0.0005394374,"domain_scores_codex":[0.9988078,0.00004012143,0.0003954255,0.0001652996,0.0004164591,0.0001748785],"domain_scores_gemma":[0.9992468,0.00007018871,0.0002044334,0.0000475907,0.0002661852,0.0001647655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000878068,0.000049871,0.9790901,0.00002795411,0.0002087126,0.0003218217,0.002884743,0.0001293527,0.005601748,0.00001212898,0.0003540125,0.01044148],"study_design_scores_gemma":[0.01000612,0.0002710448,0.9847522,0.0004885822,0.00004954359,0.00009447581,0.0003337337,0.001642747,0.001690755,0.0001986758,0.0003559077,0.0001161877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731518,0.01398507,0.00001643349,0.01202722,0.0001930808,0.0002380533,0.0002044959,0.000004832077,0.0001790146],"genre_scores_gemma":[0.9843068,0.01481417,0.0001367553,0.0003598125,0.0002870428,0.00002012431,0.000006744014,0.00001196985,0.00005655422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01166741,"threshold_uncertainty_score":0.3745194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02500203288867578,"score_gpt":0.3309872727500714,"score_spread":0.3059852398613957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}