{"id":"W3108312350","doi":"10.1039/d0lc01069c","title":"Real-time isothermal DNA amplification monitoring in picoliter volumes using an optical fiber sensor","year":2020,"lang":"en","type":"article","venue":"Lab on a Chip","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec en Outaouais","funders":"Fonds de Recherche du Québec - Santé; Narodowe Centrum Nauki; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Fonds Québécois de la Recherche sur la Nature et les Technologies; Armand-Frappier Foundation","keywords":"Loop-mediated isothermal amplification; Isothermal process; Fiber; Optical fiber; Materials science; DNA; Chemistry; Thermodynamics; Optics; Physics; Biochemistry; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008247716,0.0005692695,0.000507618,0.0003491998,0.0001831682,0.0004473156,0.0008830552,0.0007552562,0.000353156],"category_scores_gemma":[0.000998686,0.0003150297,0.0002707124,0.0003268067,0.0004508619,0.0006819268,0.0003191516,0.0006123515,0.0002622018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007197933,"about_ca_system_score_gemma":0.0005426415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001426864,"about_ca_topic_score_gemma":0.001923556,"domain_scores_codex":[0.9990821,0.00013852,0.00003772098,0.0002683811,0.000408046,0.00006519204],"domain_scores_gemma":[0.9996049,0.0001827832,0.00008944902,0.00002202184,0.00008189108,0.00001895682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003563816,0.00001473389,0.0002277062,0.00003967278,0.000004479088,0.00001389833,0.00002564236,0.0002040501,0.9955853,0.00006847642,0.00002471905,0.003755649],"study_design_scores_gemma":[0.000007234835,0.0001619947,0.0008589122,0.000004320282,0.00001534883,0.0000942562,0.00001600992,0.009787486,0.9882123,0.00004190308,0.0007837325,0.00001662847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7170952,0.002919155,0.2744935,0.0003307949,0.0001549472,0.000244479,0.0003986699,0.001753583,0.002609771],"genre_scores_gemma":[0.7543495,0.00153691,0.2403701,0.0001863507,0.00005193262,0.0002606416,0.00023208,0.00004516212,0.002967173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001426864,"threshold_uncertainty_score":0.005222559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02646033425880673,"score_gpt":0.2443097331975332,"score_spread":0.2178493989387265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}