{"id":"W3108323391","doi":"10.1136/jitc-2020-001128","title":"PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin","year":2020,"lang":"en","type":"article","venue":"Journal for ImmunoTherapy of Cancer","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Centre for Drug Research and Development; University of British Columbia","funders":"Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; National Research Foundation; Danmarks Grundforskningsfond; Stem Cell Network; Cancer Research Institute","keywords":"Podocalyxin; Cancer research; Epitope; Antigen; Cancer; Metastasis; Ovarian cancer; Antibody; Tumor microenvironment; Medicine; Biology; Kidney; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002084957,0.0007067322,0.0002773109,0.000467007,0.0001829665,0.0003261319,0.0005341272,0.0007936326,0.001747703],"category_scores_gemma":[0.0001865574,0.0001977214,0.0003266229,0.0001953527,0.0001668942,0.0002926139,0.0003807421,0.0006944351,0.0007790665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003764442,"about_ca_system_score_gemma":0.0003024444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002981366,"about_ca_topic_score_gemma":0.0003433023,"domain_scores_codex":[0.9998061,0.0000300652,0.00001130777,0.00004191828,0.00004510167,0.00006552949],"domain_scores_gemma":[0.9999068,0.00001627703,0.00001141621,0.000008932482,0.00001896573,0.00003756955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001474365,0.0002673746,0.000585544,0.00009833161,0.00001625261,0.0002251333,0.00001766058,0.0001987494,0.9840724,0.0003203096,0.0005049915,0.01354566],"study_design_scores_gemma":[0.0002779929,0.00234223,0.007486642,0.00004136024,0.00008774763,0.003507113,0.00003149145,0.006736651,0.9527344,0.0004068142,0.02632024,0.00002723043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707816,0.003636435,0.01709944,0.0005142557,0.0001363931,0.0002701552,0.0003166622,0.0003899829,0.006854993],"genre_scores_gemma":[0.9640248,0.003042505,0.02229024,0.0006838328,0.0001317032,0.0002450433,0.002331054,0.0000561811,0.007194716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001747703,"threshold_uncertainty_score":0.00584662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03868869120217639,"score_gpt":0.3684224076571678,"score_spread":0.3297337164549914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}