{"id":"W3108344241","doi":"10.1093/molbev/msaa298","title":"Frequent Assembly of Chimeric Complexes in the Protein Interaction Network of an Interspecies Yeast Hybrid","year":2020,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Université Laval; PROTEO","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Genome British Columbia; Canada Foundation for Innovation; Human Frontier Science Program","keywords":"Biology; Proteostasis; Saccharomyces cerevisiae; Phenotype; Protein–protein interaction; Yeast; Proteome; Genetics; Hybrid; Ploidy; Two-hybrid screening; Computational biology; Evolutionary biology; Gene; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003180605,0.0002751581,0.0002372181,0.0005760761,0.0002855046,0.0005150241,0.000285089,0.000414756,0.0009941733],"category_scores_gemma":[0.0006153971,0.0002185196,0.0003246732,0.0003930377,0.0002395569,0.0002630534,0.0007056954,0.0005273643,0.0002561481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002795417,"about_ca_system_score_gemma":0.0001098007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002715246,"about_ca_topic_score_gemma":0.0004668687,"domain_scores_codex":[0.9995746,0.00006140828,0.00004101064,0.0001600701,0.0001189299,0.00004402796],"domain_scores_gemma":[0.9992803,0.0001852941,0.0002201428,0.0001356069,0.00005787969,0.0001208165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008665497,0.0000138286,0.003018862,0.00001950688,0.00003991159,0.0002593579,0.00003645182,0.0001715433,0.9948925,0.0002179129,0.00002323797,0.001220167],"study_design_scores_gemma":[0.00001922478,0.0002361461,0.1360127,0.00001102148,0.000194742,0.005018161,0.0003026571,0.0096997,0.8425471,0.0009330223,0.00498672,0.00003878102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923407,0.0002257543,0.006591562,0.00002947986,0.000009428676,0.00001087373,0.0002118231,0.00007715807,0.0005032715],"genre_scores_gemma":[0.995021,0.0000681875,0.003580823,0.00002770377,0.000002740965,0.00001249443,0.0007364243,0.0000345128,0.0005160739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009941733,"threshold_uncertainty_score":0.00332582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01560043760908215,"score_gpt":0.2886446098004299,"score_spread":0.2730441721913477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}