{"id":"W3108620446","doi":"10.1158/0008-5472.can-20-1876","title":"Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada); University of Toronto","funders":"New Jersey Commission on Cancer Research; Susan G. Komen; National Cancer Institute; Rutgers Cancer Institute of New Jersey; American Cancer Society; U.S. Department of Defense","keywords":"Colorectal cancer; Cancer research; Metastasis; Medicine; Lung; Wnt signaling pathway; In vivo; Cancer; Lung cancer; Oncology; Biology; Internal medicine; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009088183,0.00018617,0.0002417144,0.0002038522,0.0000841109,0.0001767364,0.0001553368,0.0002014197,0.001165115],"category_scores_gemma":[0.00007207137,0.00006195199,0.0001548726,0.00009123793,0.0001661702,0.0001286993,0.0001164008,0.0005629194,0.0001616429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001897545,"about_ca_system_score_gemma":0.0002232207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003445118,"about_ca_topic_score_gemma":0.0008454964,"domain_scores_codex":[0.9999555,0.000008167778,0.000003074788,0.00000796589,0.00001272249,0.00001252047],"domain_scores_gemma":[0.9999627,0.000005524095,0.0000109918,0.000003821396,0.000004829002,0.00001206684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003758912,0.0001706253,0.0002251377,0.0000916059,0.00001115312,0.00005331119,0.000009258655,0.0002155238,0.990328,0.0002046656,0.0001616835,0.008153245],"study_design_scores_gemma":[0.0001470119,0.003507938,0.002405478,0.00001175639,0.00003707899,0.0003513058,0.00002529378,0.002158067,0.9844095,0.0001379098,0.006802537,0.000006191996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867396,0.005044342,0.003808846,0.0002921781,0.0001131645,0.00009878504,0.0002768763,0.0002297325,0.003396577],"genre_scores_gemma":[0.9954879,0.00111861,0.001402103,0.00006303817,0.00001507498,0.00003393469,0.0001125836,0.000007334329,0.001759391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001165115,"threshold_uncertainty_score":0.003897727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0930725144396463,"score_gpt":0.4532038766076852,"score_spread":0.3601313621680389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}