{"id":"W3108642522","doi":"10.1016/j.lungcan.2020.11.015","title":"A reply to “Correspondence Re: Development, validation and results from the impact of treatment evolution in non-small cell lung cancer (iTEN) model”","year":2020,"lang":"en","type":"letter","venue":"Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"EVERSANA (Canada); Saskatchewan Cancer Agency; Mount Sinai Hospital; McMaster University; Alberta Cancer Foundation; William Osler Health System; AstraZeneca (Canada)","funders":"AstraZeneca Canada","keywords":"Medicine; Lung cancer; Cancer; Oncology; Internal medicine; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001079769,0.0004611411,0.0006309439,0.0001843787,0.0001083939,0.00004237893,0.0001608441,0.0002520765,0.00008225018],"category_scores_gemma":[0.00005709382,0.0003066693,0.0001565088,0.0004517896,0.00004115574,0.0001057816,0.00006593382,0.000471726,0.000004721686],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00626225,"about_ca_system_score_gemma":0.003416977,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.06714196,"about_ca_topic_score_gemma":0.001990573,"domain_scores_codex":[0.9976479,0.00007865847,0.0007122816,0.0008303256,0.0003360112,0.0003947739],"domain_scores_gemma":[0.9985054,0.0001980489,0.0004368124,0.0005407583,0.0001788307,0.0001402071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001761658,0.0001192739,0.07097944,0.0003700995,0.001331125,0.0001090565,0.02169586,0.01794582,0.001228308,9.469575e-7,0.8821323,0.002326145],"study_design_scores_gemma":[0.04706428,0.003371051,0.4555808,0.02060045,0.01613393,0.00002834011,0.001046472,0.2200774,0.009154912,0.0002441243,0.2225653,0.004132859],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.526874,0.01336288,0.002065496,0.4417519,0.0008804412,0.007681878,0.005900591,0.0001125904,0.00137022],"genre_scores_gemma":[0.7334366,0.003440909,0.003672244,0.2285256,0.00338035,0.005200163,0.004596149,0.0002913369,0.01745662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6595669,"threshold_uncertainty_score":0.9999385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02411262466697046,"score_gpt":0.3370667255501405,"score_spread":0.31295410088317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}