{"id":"W3108672196","doi":"10.1016/j.molimm.2020.11.011","title":"Antigen presentation genes in gadoid species (haddock: Melanogrammus aeglefinus and Atlantic cod: Gadus morhua) raise questions about cross-presentation pathways and glycosylated beta-2-microglobulin","year":2020,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland; University of Waterloo","funders":"Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Haddock; Biology; Antigen presentation; Major histocompatibility complex; Gadus; Antigen processing; MHC class I; Antigen; Genetics; Immune system; T cell; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009625906,0.0001879721,0.0001243625,0.0003024335,0.0002100847,0.0003104261,0.0001243186,0.0002974382,0.000943768],"category_scores_gemma":[0.0002299121,0.00009995681,0.0001733649,0.0001734029,0.0002572651,0.0001920516,0.0003009117,0.0003868695,0.0001511197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003901548,"about_ca_system_score_gemma":0.0001752446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002755538,"about_ca_topic_score_gemma":0.005225656,"domain_scores_codex":[0.9999176,0.000006571989,0.00000541497,0.00003755882,0.000007160546,0.00002567462],"domain_scores_gemma":[0.9998176,0.0000363961,0.00005919136,0.000012938,0.00002279561,0.00005108769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005481172,0.00002927785,0.04483055,0.00004895609,0.00002731509,0.0001408984,0.0002751112,0.00005978454,0.9497876,0.0001540464,0.00007692199,0.004021523],"study_design_scores_gemma":[0.00002677661,0.0003453999,0.9362336,0.00001781514,0.00006178772,0.0007438189,0.0008691742,0.000389141,0.05959385,0.0002176754,0.001487226,0.00001382805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999442,0.00009115761,0.0001150154,0.00002701188,0.000004911474,0.000001473347,0.000135987,0.000003216097,0.0001792313],"genre_scores_gemma":[0.9982471,0.0001007522,0.0003899283,0.00009094144,0.000004433758,0.000005498228,0.0003747271,0.000006123991,0.0007803889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002755538,"threshold_uncertainty_score":0.005478978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425637602948076,"score_gpt":0.2420696305300397,"score_spread":0.2278132545005589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}