{"id":"W3108677307","doi":"10.3899/jrheum.200951","title":"Metaanalysis Reveals Genetic Correlates of Osteoporosis Pathogenesis","year":2020,"lang":"en","type":"review","venue":"The Journal of Rheumatology","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Cancer Institute","keywords":"Medicine; Osteoporosis; Wnt signaling pathway; Bioinformatics; Signal transduction; Internal medicine; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001243143,0.0005062724,0.004801413,0.000438035,0.0001137161,0.000007161143,0.001540917,0.0008625328,0.0007973882],"category_scores_gemma":[0.0005793895,0.0002973198,0.001724521,0.0005797282,0.0004688922,0.00003766627,0.0002845549,0.0007930535,0.0002502227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005968464,"about_ca_system_score_gemma":0.0004151887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002479177,"about_ca_topic_score_gemma":0.000004285411,"domain_scores_codex":[0.9933429,0.00334605,0.002574134,0.000253786,0.0001122536,0.0003709143],"domain_scores_gemma":[0.9924865,0.001707962,0.004828248,0.0006589449,0.0002530913,0.00006522989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003241118,0.000196227,0.001353663,0.00872632,0.02454217,0.0000662174,0.0005432278,0.000003783242,0.001190075,0.0002835385,0.00757548,0.9551952],"study_design_scores_gemma":[0.001416996,0.0008944264,0.0001242983,0.01087355,0.0738029,0.05000616,0.0005956526,0.000002393367,0.0003239625,0.001304741,0.8597709,0.0008840422],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0019411,0.9959618,0.000290455,0.00008960097,0.001263828,0.0003036023,0.0001089747,0.00001432697,0.00002626859],"genre_scores_gemma":[0.003333198,0.9959683,0.000472019,0.00003141684,0.0000079871,0.000009799556,0.00002800522,0.00005896361,0.00009025695],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9543111,"threshold_uncertainty_score":0.9999479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095952762173404,"score_gpt":0.2665717792645131,"score_spread":0.2456122516427791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}