{"id":"W3108724287","doi":"10.1158/2326-6074.tumimm18-pr19","title":"Abstract PR19: Utilizing novel oncolytic vaccinia virus for selective expression of immunotherapeutic payloads in metastatic tumors","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Oncolytic virus; Vaccinia; Immune system; Immune checkpoint; Immunotherapy; Cancer; Medicine; Cancer research; Cancer immunotherapy; Immunology; Virus; Biology; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001663356,0.0003461287,0.0002089837,0.0001759166,0.0001352082,0.0003473409,0.0002670631,0.0003329577,0.001241163],"category_scores_gemma":[0.0001133549,0.000122137,0.00030038,0.0001025334,0.0001865028,0.0002819053,0.0002294859,0.000516072,0.0005429685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003923633,"about_ca_system_score_gemma":0.0002124216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006324277,"about_ca_topic_score_gemma":0.0004641418,"domain_scores_codex":[0.9999006,0.00001037748,0.000007488668,0.00002520921,0.0000277031,0.00002869184],"domain_scores_gemma":[0.9999502,0.000006320939,0.00001611713,0.000006072003,0.000009424416,0.00001196239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000851095,0.00005054159,0.0001056606,0.00003460401,0.000004651545,0.00007520126,0.000007652903,0.0002057954,0.99595,0.0004308753,0.0001365801,0.002913254],"study_design_scores_gemma":[0.00003142377,0.0003161328,0.0004470533,0.000004170466,0.00001017925,0.0002722803,0.000004423137,0.001801742,0.9920673,0.00006297056,0.004978261,0.000003953088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9501224,0.003601442,0.03912885,0.0003067886,0.0002170852,0.0002781396,0.0006789165,0.0003488393,0.005317528],"genre_scores_gemma":[0.9730883,0.001581164,0.01912452,0.00008964405,0.00003404017,0.00008075327,0.0007476506,0.00008082324,0.00517316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001241163,"threshold_uncertainty_score":0.004152179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139896027847282,"score_gpt":0.4195886685095294,"score_spread":0.3055990657248012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}