{"id":"W3108852904","doi":"10.1016/s1470-2045(20)30561-1","title":"Drug repurposing in oncology","year":2020,"lang":"en","type":"letter","venue":"The Lancet Oncology","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada; Astellas Pharma; Merck Sharp and Dohme; EMD Serono; Ipsen; Pfizer","keywords":"Drug repositioning; Repurposing; Medicine; Drug; Alternative medicine; Scopus; Pharmacology; Oncology; MEDLINE; Internal medicine; Pathology; Political science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01004381,0.001256898,0.001978009,0.001426904,0.007244137,0.008664466,0.002637952,0.1078737,0.01313947],"category_scores_gemma":[0.06185297,0.001397778,0.002265687,0.001363159,0.007444355,0.006309627,0.004323847,0.05938367,0.009953856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008769397,"about_ca_system_score_gemma":0.0119975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01550856,"about_ca_topic_score_gemma":0.03086146,"domain_scores_codex":[0.9896641,0.003942307,0.0007868913,0.0008814723,0.003472527,0.001252582],"domain_scores_gemma":[0.9539387,0.03319905,0.001460192,0.001090443,0.004087541,0.006224146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003306884,0.00001942759,0.0001324757,0.00003396601,0.00001191897,0.0001500529,0.00004233674,0.00009938972,0.00006047517,0.006224783,0.9856871,0.007505056],"study_design_scores_gemma":[0.0002232808,0.00008058848,0.0005347843,0.0004285902,0.00003393399,0.0003088483,0.000148193,0.001757652,0.0002007475,0.05649162,0.9397253,0.00006649131],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001126152,0.001821892,0.0001528274,0.981307,0.01309221,0.00001469907,0.00005586062,0.00002080114,0.00342204],"genre_scores_gemma":[0.001769235,0.001442489,0.0002585092,0.9610422,0.02708571,0.000048588,0.00003596313,0.00002276492,0.008294535],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1078737,"threshold_uncertainty_score":0.06362671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08677252661125053,"score_gpt":0.37699662881572,"score_spread":0.2902241022044695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}