{"id":"W3108854688","doi":"10.1016/j.jaad.2020.06.152","title":"14020 Durability of responses with bimekizumab, a selective dual inhibitor of interleukin-17A and -17F, in moderate to severe chronic plaque psoriasis in a 60-week randomized, double-blinded, phase 2b study (BE ABLE 2)","year":2020,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health; Probity Medical Research","funders":"","keywords":"Medicine; Post-hoc analysis; Plaque psoriasis; Psoriasis; Internal medicine; Post hoc; Gastroenterology; Randomized controlled trial; Surgery; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001766231,0.001043926,0.002260285,0.0003496437,0.0003210111,0.0009126746,0.0005757051,0.001329973,0.005943545],"category_scores_gemma":[0.0008121537,0.0005582809,0.001313647,0.0002479687,0.0007278863,0.0008497273,0.0003020217,0.002208955,0.001097688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003853137,"about_ca_system_score_gemma":0.0006214645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004577861,"about_ca_topic_score_gemma":0.0008018811,"domain_scores_codex":[0.9995247,0.000187271,0.0000242478,0.00008281072,0.00005127487,0.0001297146],"domain_scores_gemma":[0.9995172,0.0001168552,0.00007660099,0.00004470807,0.00002996178,0.0002146968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8944585,0.02279122,0.001271045,0.0006964686,0.0008642336,0.00005478529,0.00008036045,0.0005676546,0.02505143,0.000169075,0.001998297,0.05199699],"study_design_scores_gemma":[0.7734698,0.2169565,0.005338086,0.00002532941,0.0003243509,0.0000771001,0.00002382544,0.0004348191,0.002171783,0.0001470897,0.001009423,0.00002182169],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929004,0.002667279,0.0004864729,0.000267945,0.0002286424,0.000905022,0.0009412876,0.0001084482,0.001494452],"genre_scores_gemma":[0.9888991,0.001674859,0.000998562,0.0009189355,0.0003441279,0.001374298,0.001314666,0.00003753637,0.00443789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005943545,"threshold_uncertainty_score":0.0198831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03296586563614887,"score_gpt":0.3059289460698301,"score_spread":0.2729630804336812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}