{"id":"W3109045415","doi":"10.1038/s41467-020-19876-6","title":"Cohesin depleted cells rebuild functional nuclear compartments after endomitosis","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; Deutsche Forschungsgemeinschaft; Ludwig-Maximilians-Universität München; International Max Planck Research School for Advanced Methods in Process and Systems Engineering; International Max Planck Research School for Environmental, Cellular and Molecular Microbiology; U.S. Department of Agriculture; Deutsches Krebsforschungszentrum; Welch Foundation; Institute of Genetics; National Institutes of Health; National Science Foundation","keywords":"Cohesin; Chromatin; Cell biology; Biology; Cell nucleus; Replication timing; CTCF; Chromosome segregation; Chromosome; Nucleus; Genetics; DNA; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005474646,0.0001515899,0.0002327789,0.0001658511,0.00009595425,0.0003047722,0.0001161806,0.0002070655,0.0009151567],"category_scores_gemma":[0.0000906905,0.0001128085,0.0001233722,0.0001196864,0.0001753666,0.0001359549,0.0001923771,0.0003805149,0.0003641515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002097599,"about_ca_system_score_gemma":0.0001763374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001413374,"about_ca_topic_score_gemma":0.001612862,"domain_scores_codex":[0.9999267,0.000005061558,0.000007238692,0.00001875528,0.00002483811,0.00001744569],"domain_scores_gemma":[0.9998672,0.00002455536,0.00001917675,0.00002711578,0.00001853226,0.00004349477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004341033,0.000004566487,0.0001978237,0.000009260812,0.000002652167,0.00006153533,0.00001853275,0.00002353117,0.9991422,0.00005687496,0.00001416912,0.0004256219],"study_design_scores_gemma":[0.000008657738,0.0001199438,0.0150247,0.000004160507,0.000007245382,0.0003113524,0.00008190937,0.0005362634,0.981371,0.00005106155,0.002479066,0.000004564731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957825,0.0005764704,0.002206436,0.00004275583,0.00001870591,0.000009562613,0.0003730053,0.00007213371,0.0009183349],"genre_scores_gemma":[0.994615,0.0002019587,0.001011758,0.00003346585,0.000003505076,0.00001174836,0.0006711746,0.00002301856,0.003428312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001413374,"threshold_uncertainty_score":0.003061533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01313016377613391,"score_gpt":0.231450335876093,"score_spread":0.2183201720999591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}