{"id":"W3109126528","doi":"10.1210/endrev/bnaa028","title":"Progress in Translational Regulatory T Cell Therapies for Type 1 Diabetes and Islet Transplantation","year":2020,"lang":"en","type":"review","venue":"Endocrine Reviews","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Breakthrough T1D Canada; Juvenile Diabetes Research Foundation Canada; Alberta Health Services","keywords":"Transplantation; Islet; Immunology; Context (archaeology); Medicine; Alloimmunity; Type 1 diabetes; Immune system; Islet cell transplantation; Disease; Biology; Bioinformatics; Diabetes mellitus; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003049645,0.0007334939,0.001062809,0.00111403,0.0003481333,0.001524112,0.0007933162,0.001513184,0.00450064],"category_scores_gemma":[0.001493672,0.0002413154,0.0008634737,0.0008351814,0.0008396739,0.002101478,0.001128836,0.00405383,0.001430814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005707213,"about_ca_system_score_gemma":0.002425615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004419658,"about_ca_topic_score_gemma":0.0007237238,"domain_scores_codex":[0.9993804,0.0001838306,0.00008712676,0.00007416189,0.0001908785,0.00008364169],"domain_scores_gemma":[0.9989986,0.0005345579,0.0001059967,0.00004633685,0.000209172,0.0001054052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003028488,0.0003514218,0.0003582313,0.01616308,0.00009664216,0.0005788556,0.0003613708,0.0007732165,0.01791479,0.02376171,0.02737796,0.9119598],"study_design_scores_gemma":[0.0001210914,0.0008215917,0.0006313929,0.004365197,0.0001540062,0.001034946,0.000170309,0.0003253317,0.005466867,0.01097456,0.9758976,0.00003707152],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001337943,0.9850463,0.00352634,0.003753907,0.001909765,0.00005066078,0.00006108997,0.00005945443,0.004254656],"genre_scores_gemma":[0.007588022,0.9807709,0.00514339,0.003052577,0.00197619,0.00009185063,0.0001869323,0.00001985492,0.001170263],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00450064,"threshold_uncertainty_score":0.01612824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06718375829279748,"score_gpt":0.3568472444885536,"score_spread":0.2896634861957561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}