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Università degli Studi di Verona; Khalifa University of Science, Technology and Research; Pennsylvania State University; Lunds Universitet; Horizon 2020 Framework Programme; Universiteit Utrecht; Medical Research Council; Servier; University of Bristol; Imperial College London; National Human Genome Research Institute; Kidney Research UK; Department of Health and Social Care; University of Cambridge; British Heart Foundation; Stichting de Drie Lichten; Isaac Newton Trust; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Barts Charity; U.S. Department of Health and Human Services; Genomic Health; Vanderbilt University Medical Center; National Cancer Institute; University College London; Cancer Research UK; Wellcome Trust; Gentofte Hospital; National Institute for Health and Care Research; University of North Carolina at Chapel Hill; Queen Mary University of London; Pfizer; University of Washington; National Institute on Minority Health and Health Disparities; AstraZeneca; Genentech; School of Public Health, Imperial College London; University of Oxford; Amgen; Novo Nordisk; Li Ka Shing Foundation; School of Medicine, Boston University; Cambridge University Hospitals; University of Pennsylvania; Vanderbilt University; International Seafood Sustainability Foundation; Biogen; Government of the United Kingdom; University of Michigan; UK Research and Innovation; Eli Lilly and Company","keywords":"Biology; Meta-analysis; Computational biology; Genetics; Blood pressure; Evolutionary biology; Bioinformatics; Internal medicine; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002324412,0.0009722105,0.002430156,0.001224151,0.0001140032,0.0009117941,0.001018733,0.001053855,0.001999577],"category_scores_gemma":[0.003666303,0.0003648907,0.002191248,0.001757817,0.000251505,0.0004716066,0.0007097066,0.001329998,0.0005869681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000338412,"about_ca_system_score_gemma":0.001433817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001540644,"about_ca_topic_score_gemma":0.003434822,"domain_scores_codex":[0.9993193,0.0002088026,0.0001163237,0.0001655281,0.0001453301,0.00004476863],"domain_scores_gemma":[0.9979978,0.001485734,0.0002016697,0.00007238159,0.0001814379,0.00006090557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001177374,0.00004931608,0.01048085,0.03701863,0.02110318,0.001078,0.00009852954,0.0007685038,0.002649854,0.00267059,0.03016157,0.8927436],"study_design_scores_gemma":[0.001419896,0.0007848146,0.08509086,0.02977059,0.1002594,0.01037978,0.0002293453,0.001255733,0.002999283,0.0189719,0.7485139,0.0003245221],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0009531418,0.9968848,0.0006367512,0.0006864523,0.0002478139,0.000005550147,0.0002647058,0.00002338355,0.0002974292],"genre_scores_gemma":[0.008819527,0.9866252,0.001584925,0.001303742,0.0005834429,0.00002126752,0.000640618,0.00001707069,0.0004041601],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002430156,"threshold_uncertainty_score":0.01229286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04167368506031807,"score_gpt":0.3203020398534679,"score_spread":0.2786283547931498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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