{"id":"W3109233783","doi":"10.1136/gutjnl-2020-iddf.141","title":"IDDF2020-ABS-0058 48-week safety and efficacy of switching to tenofovir alafenamide (TAF) from tenofovir disoproxil fumarate (TDF) in chronic HBV asian patients with TDF risk factors (RF)","year":2020,"lang":"en","type":"article","venue":"Abstracts","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Tenofovir alafenamide; Medicine; Internal medicine; Gastroenterology; Urology; Adverse effect; Tenofovir; Creatinine; Viral load; Human immunodeficiency virus (HIV); Antiretroviral therapy; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009370039,0.0005943439,0.00147249,0.0002281714,0.0002949861,0.0004972554,0.0004406693,0.001052978,0.005003811],"category_scores_gemma":[0.0009298969,0.0002808652,0.0009809452,0.000171912,0.000436899,0.0005099042,0.0002452825,0.001951723,0.001166382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000456195,"about_ca_system_score_gemma":0.0006019194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007959502,"about_ca_topic_score_gemma":0.001074947,"domain_scores_codex":[0.9996431,0.0001398844,0.00002982984,0.00006651859,0.00004321955,0.00007748052],"domain_scores_gemma":[0.9993686,0.0001174482,0.0001453188,0.00008533146,0.00004611279,0.000237198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8361351,0.03389803,0.005879133,0.0001998951,0.0003282463,0.00008026091,0.00008042571,0.0005710551,0.01820275,0.00008182456,0.002162159,0.1023812],"study_design_scores_gemma":[0.3730094,0.579495,0.03705065,0.00005927706,0.0003317725,0.0001682676,0.00004427022,0.001551247,0.005425632,0.0001886273,0.002637373,0.00003847999],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962226,0.0006454654,0.0001979,0.0001478782,0.00008843878,0.0004559312,0.0007802474,0.00006998646,0.001391534],"genre_scores_gemma":[0.9951698,0.0002898824,0.0004789139,0.0003710287,0.0001053354,0.0007318932,0.0008712118,0.00001224504,0.001969556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005003811,"threshold_uncertainty_score":0.01673943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01488344569709511,"score_gpt":0.2388066593021546,"score_spread":0.2239232136050595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}