{"id":"W3109562861","doi":"10.1038/s42003-020-01448-5","title":"Type I toxin-antitoxin systems contribute to the maintenance of mobile genetic elements in Clostridioides difficile","year":2020,"lang":"en","type":"article","venue":"Communications Biology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Université de Paris; Institut Universitaire de France; Centre National de la Recherche Scientifique; Russian Foundation for Basic Research; Agence Nationale de la Recherche","keywords":"Antitoxin; Prophage; Biology; Mobile genetic elements; Toxin; Microbiology; Gene; Genetics; Plasmid; Escherichia coli; Bacteriophage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021518,0.0003020692,0.00016686,0.0003025554,0.000311339,0.0003197406,0.0001232763,0.0002205012,0.0005062811],"category_scores_gemma":[0.0002258203,0.0001328201,0.0002138182,0.0002994328,0.0001781257,0.0001415648,0.0002716351,0.0003988681,0.0002138141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002849037,"about_ca_system_score_gemma":0.0002573686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001386478,"about_ca_topic_score_gemma":0.001381236,"domain_scores_codex":[0.9998866,0.0000115023,0.000009651364,0.00002161194,0.00003801324,0.00003260645],"domain_scores_gemma":[0.9997932,0.0000381259,0.00006554677,0.00001848542,0.00003360103,0.0000509838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003850145,0.000006329774,0.0008112685,0.00001552993,0.000001290274,0.00004707432,0.00002103022,0.0000305661,0.9976847,0.00004982629,0.000008344934,0.001285516],"study_design_scores_gemma":[0.00001392706,0.0003044137,0.05021213,0.00001860557,0.00003960987,0.001005848,0.0001784399,0.0005781189,0.9446115,0.0001573227,0.002869183,0.00001087958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955809,0.0007177306,0.002881182,0.00005115864,0.00001437875,0.00001116862,0.0001162658,0.00002542085,0.0006018865],"genre_scores_gemma":[0.9942855,0.0003913559,0.00396,0.00002545357,0.000006219963,0.00001002251,0.0003100758,0.00001114546,0.001000256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001386478,"threshold_uncertainty_score":0.002756774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05651382217798276,"score_gpt":0.3474004861077952,"score_spread":0.2908866639298124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}