{"id":"W3109685830","doi":"10.1176/appi.ajp.2020.20030299","title":"The Case for Cautious Interpretation and Replication: Lead-Time Bias as a Potential Explanation for the Link Between Duration of Untreated Psychosis and Outcome","year":2020,"lang":"en","type":"letter","venue":"American Journal of Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Douglas Mental Health University Institute","funders":"","keywords":"Duration (music); Replication (statistics); Psychosis; Outcome (game theory); Psychology; Interpretation (philosophy); Link (geometry); Psychiatry; Lead (geology); Meta-analysis; Medicine; Computer science; Economics; Internal medicine; Biology; Microeconomics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1208,0.001700702,0.003390996,0.00239072,0.006820714,0.01068432,0.01068182,0.04437673,0.005169977],"category_scores_gemma":[0.4199208,0.0009867657,0.002460135,0.002633115,0.01612976,0.01113465,0.003964757,0.04743632,0.005242702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005233393,"about_ca_system_score_gemma":0.01058109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006903884,"about_ca_topic_score_gemma":0.00686008,"domain_scores_codex":[0.9134594,0.05031338,0.00900643,0.007573078,0.0177939,0.001853903],"domain_scores_gemma":[0.5924199,0.3215358,0.015583,0.02241893,0.0432702,0.004772182],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002780187,0.0001091314,0.004950549,0.0005506315,0.0001656604,0.001908129,0.001910039,0.0002088121,0.0002128221,0.01980161,0.9313281,0.03857661],"study_design_scores_gemma":[0.0006839914,0.0003094775,0.007398599,0.004338283,0.0005176875,0.005888288,0.006487725,0.01095678,0.001459861,0.3045879,0.6568917,0.0004798564],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005852183,0.001383423,0.001670666,0.9561678,0.03910474,0.00004256115,0.00007369225,0.00005914651,0.0009128606],"genre_scores_gemma":[0.01536416,0.002166846,0.006399177,0.8526796,0.1209993,0.0002366921,0.00005157981,0.0000790476,0.002023564],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.8792,"threshold_uncertainty_score":0.6388589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02895222632332717,"score_gpt":0.334233730508577,"score_spread":0.3052815041852499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}