{"id":"W3109739095","doi":"10.1136/annrheumdis-2020-218870","title":"Upadacitinib for psoriatic arthritis refractory to biologics: SELECT-PsA 2","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":233,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"AbbVie; Genentech; Celgene; Gilead Sciences; Amgen; Pfizer; Eli Lilly and Company","keywords":"Medicine; Placebo; Psoriatic arthritis; Internal medicine; Adverse effect; Rheumatology; Clinical endpoint; Arthritis; Pharmacology; Gastroenterology; Urology; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006319665,0.0001605059,0.0004788521,0.00003075339,0.000115678,0.0000121947,0.0001414697,0.00003486018,0.0001210817],"category_scores_gemma":[0.001792231,0.0001032955,0.0002942177,0.0001978556,0.00006791403,0.00004092878,0.00007788656,0.00004532292,0.00004102364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001018165,"about_ca_system_score_gemma":0.00006999539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000196376,"about_ca_topic_score_gemma":0.000005464359,"domain_scores_codex":[0.9989334,0.00003921627,0.0003422002,0.0002191343,0.0002043054,0.0002617823],"domain_scores_gemma":[0.998976,0.0002142175,0.0001417087,0.0002696803,0.000158118,0.0002402759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002217516,0.001654723,0.01606462,0.001532469,0.002116356,0.00002672749,0.002073022,0.00002812741,0.0003027548,0.001899577,0.2036303,0.7684538],"study_design_scores_gemma":[0.03426491,0.02621952,0.6626928,0.01377899,0.002997956,0.00007736385,0.005391742,0.0008756603,0.01540818,0.03038036,0.2057163,0.002196132],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9599394,0.01295628,0.0001107339,0.02363577,0.0002492256,0.001737675,0.0007101613,0.00008232739,0.0005784321],"genre_scores_gemma":[0.9923464,0.001798115,0.0003755886,0.005065812,0.00009169863,0.0001615666,0.00003378292,0.00001940371,0.0001076296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7662576,"threshold_uncertainty_score":0.4212269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07046193175246603,"score_gpt":0.3277423721760776,"score_spread":0.2572804404236116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}