{"id":"W3109767421","doi":"","title":"Potential Role of Extracellular Granzyme B in the Pathogenesis of Age-related Macular Degeneration (AMD)","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia","funders":"","keywords":"Macular degeneration; Pathogenesis; Granzyme B; Extracellular; Medicine; Ophthalmology; Pathology; Immunology; Biology; Cell biology; Immune system; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005115593,0.0001331114,0.0002856193,0.0001534363,0.00006539511,0.000008668544,0.0002190519,0.00007902179,0.0001199466],"category_scores_gemma":[0.0001176051,0.00008940489,0.00009743615,0.0007952091,0.00167577,0.0001134894,0.00005159586,0.0001004369,0.00002051064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003616996,"about_ca_system_score_gemma":0.0002064119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001774756,"about_ca_topic_score_gemma":9.181159e-7,"domain_scores_codex":[0.9984046,0.00020882,0.0003457915,0.0003348497,0.0004709057,0.0002349885],"domain_scores_gemma":[0.9992737,0.00004834899,0.0001932861,0.0002348998,0.0001458982,0.0001039346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005377422,0.000256755,0.2176812,0.00001913486,0.00001716043,0.0003253671,0.0004411714,0.00008477219,0.7804757,0.0005227277,6.116065e-7,0.0001216096],"study_design_scores_gemma":[0.0005577337,0.0008097824,0.6685792,0.00005102352,0.00006505875,0.0001938166,0.0003512841,0.0009746809,0.3253166,0.003034665,0.000001744432,0.00006441873],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978588,0.000730713,0.000001266816,0.0001041918,0.00006345369,0.0005083308,0.00000859891,0.000005180675,0.0007195107],"genre_scores_gemma":[0.9994763,0.000007479048,0.0003312044,0.00003227478,0.00001038738,0.0000176228,0.00002244001,0.000007385685,0.00009493736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4551591,"threshold_uncertainty_score":0.6174444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843516181562976,"score_gpt":0.3036992307405874,"score_spread":0.2852640689249576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}