{"id":"W3109792347","doi":"10.1186/s13229-020-00394-7","title":"The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior","year":2020,"lang":"en","type":"article","venue":"Molecular Autism","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; Carleton University; Centre in Green Chemistry and Catalysis; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Brain Canada; McGill University; Brain and Behavior Research Foundation; Howard Hughes Medical Institute","keywords":"Depression (economics); Neurology; Hippocampal formation; Term (time); Neuropsychology; Neuroscience; Medicine; EIF4E; Psychology; Psychiatry; Biology; Genetics; Economics; Cognition; Gene; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000153989,0.0002698182,0.0002005819,0.00002075648,0.0003596327,0.0001079774,0.000351072,0.0002606587,0.00002215457],"category_scores_gemma":[0.00008362714,0.0002226564,0.0001455957,0.00009869884,0.0002643832,0.00000700773,0.0003194973,0.000221872,0.00001133037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002548815,"about_ca_system_score_gemma":0.00009486507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001255315,"about_ca_topic_score_gemma":0.000009384962,"domain_scores_codex":[0.9983804,0.0001322275,0.0002437946,0.0005518048,0.0002431004,0.0004487111],"domain_scores_gemma":[0.9992566,0.00001828159,0.0001234146,0.0003524294,0.00004039479,0.0002089549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000949224,0.00002886256,0.006212689,0.00001742612,0.00007369526,0.0001361853,0.0001247135,0.000007500203,0.979341,0.00009744708,0.001198157,0.01266743],"study_design_scores_gemma":[0.001207601,0.0005034978,0.3150155,0.00003476924,0.0001568818,0.0001421865,0.00002338544,0.00007108692,0.678888,0.0002392402,0.003171112,0.0005467216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907295,0.005978572,0.000969958,0.001598339,0.0002078327,0.0003004546,0.00002421929,0.00004403411,0.0001470883],"genre_scores_gemma":[0.9982848,0.0001974318,0.000135344,0.0009592365,0.0001233129,0.00006199439,0.00008333729,0.00005684571,0.00009768731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3088028,"threshold_uncertainty_score":0.9079664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01035432811854087,"score_gpt":0.2631309800641783,"score_spread":0.2527766519456374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}