{"id":"W3109944840","doi":"10.1002/mds.28399","title":"Immunohistochemical Detection of Synuclein Pathology in Skin in Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Parkinsonism","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital du Sacré-Cœur de Montréal; McGill University Health Centre; McGill University; Montreal General Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; Arizona Department of Health Services","keywords":"Parkinsonism; Pathology; Alpha-synuclein; Medicine; Parkinson's disease; Lewy body; Autopsy; Immunohistochemistry; Pathological; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006281859,0.0002353462,0.0001801791,0.0007184569,0.0001837665,0.0002032691,0.0001615566,0.0003232358,0.00117713],"category_scores_gemma":[0.0006740688,0.0001800057,0.0001166699,0.0002059738,0.0003104933,0.0001569873,0.0001844107,0.0001251146,0.0002417705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001435355,"about_ca_system_score_gemma":0.00006705304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003215193,"about_ca_topic_score_gemma":0.0007246286,"domain_scores_codex":[0.9996607,0.000107791,0.00003758915,0.00009415072,0.00006645014,0.00003324078],"domain_scores_gemma":[0.9995447,0.0001219553,0.0001421893,0.00004737964,0.00008668827,0.00005708724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000916481,0.0001516771,0.5691182,0.000146479,0.0001046659,0.002866759,0.0002607483,0.0001847295,0.4153246,0.00004954099,0.0001078573,0.01076824],"study_design_scores_gemma":[0.00004134528,0.0006726523,0.9605736,0.0000147732,0.00004881109,0.01155696,0.0001784419,0.0006192044,0.02595266,0.0000494104,0.0002863159,0.000005926282],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987599,0.0003495124,0.0004440788,0.000005869711,0.000003223799,0.00001182214,0.00002857025,0.000007094025,0.0003898831],"genre_scores_gemma":[0.9984769,0.0001326848,0.001130495,0.0000175394,0.000005227768,0.000009844072,0.00006894605,0.000001577615,0.0001567583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00117713,"threshold_uncertainty_score":0.0039379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007885754699006854,"score_gpt":0.237524058729682,"score_spread":0.2296383040306751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}