{"id":"W3110000759","doi":"10.3389/fimmu.2020.575607","title":"Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF","year":2020,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Institut de Cardiologie de Montréal; Canada Foundation for Innovation; Canadian Vascular Network","keywords":"Platelet; Platelet activation; Cell biology; Chemistry; Brain-derived neurotrophic factor; Neuroscience; Internal medicine; Medicine; Biology; Biochemistry; Neurotrophic factors; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008099605,0.0001869048,0.0001418688,0.0001674126,0.00009508883,0.0002863639,0.00007330473,0.0002288134,0.001440892],"category_scores_gemma":[0.000308145,0.0000880662,0.0001308118,0.0001030742,0.0001361516,0.0001221287,0.0001150284,0.0002845073,0.0002795196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001287416,"about_ca_system_score_gemma":0.00006895968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004326377,"about_ca_topic_score_gemma":0.0003306381,"domain_scores_codex":[0.9998978,0.00001650877,0.000008539069,0.00002656438,0.00002957573,0.00002092085],"domain_scores_gemma":[0.9998881,0.00003417243,0.00003570075,0.000007866925,0.00001877802,0.00001532407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007091906,0.0000232472,0.001716271,0.00008153125,0.00001205207,0.0002707645,0.00005593822,0.0000260476,0.992588,0.00005980566,0.0001842462,0.00427292],"study_design_scores_gemma":[0.0001717138,0.001618124,0.1607216,0.00006957478,0.0001400189,0.004720503,0.0002107394,0.001467986,0.8240052,0.0004026063,0.006456182,0.00001575226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928212,0.003537602,0.001689609,0.0001307349,0.00002937999,0.00003913603,0.0004159104,0.00004000753,0.001296579],"genre_scores_gemma":[0.9964335,0.001119832,0.000964886,0.00008629343,0.00002516012,0.00005077086,0.0003614725,0.00001070692,0.0009474317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001440892,"threshold_uncertainty_score":0.004820228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0287739300233134,"score_gpt":0.2329534119161677,"score_spread":0.2041794818928543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}