{"id":"W3110000759","doi":"10.3389/fimmu.2020.575607","title":"Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF","year":2020,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Institut de Cardiologie de Montréal; Canada Foundation for Innovation; Canadian Vascular Network","keywords":"Platelet; Platelet activation; Cell biology; Chemistry; Brain-derived neurotrophic factor; Neuroscience; Internal medicine; Medicine; Biology; Biochemistry; Neurotrophic factors; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609405,0.000141885,0.0003088397,0.0000968146,0.00007828027,0.000008132594,0.0004249352,0.0001516879,0.0000143747],"category_scores_gemma":[0.0004478916,0.0001047133,0.00006867388,0.0004021016,0.0003884114,0.0001562825,0.0000907897,0.0003050561,0.000007338898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003060748,"about_ca_system_score_gemma":0.0000900204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001070987,"about_ca_topic_score_gemma":0.000002256916,"domain_scores_codex":[0.9984584,0.0004342448,0.000348444,0.0003438119,0.0001668056,0.0002482896],"domain_scores_gemma":[0.999308,0.00006137269,0.0003103725,0.000236,0.0000561741,0.00002810217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009722511,0.00006685312,0.0001797788,0.00005592581,0.00002293577,0.000009550498,0.0007777775,0.000144646,0.991443,0.001495917,0.0007542664,0.004077087],"study_design_scores_gemma":[0.0005718751,0.0004225734,0.0009859366,0.0000367848,0.000009738485,0.00001022349,0.0000916482,0.001157385,0.9947127,0.0005142608,0.001381216,0.0001056755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938647,0.0008135326,0.001058111,0.002414166,0.0005051208,0.0009400963,0.00002758139,0.00003141832,0.000345313],"genre_scores_gemma":[0.9981742,0.0001296774,0.0007083496,0.0002368164,0.00003442699,0.00006761854,0.000002434529,0.00001644446,0.0006300508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00430952,"threshold_uncertainty_score":0.4270082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0287739300233134,"score_gpt":0.2329534119161677,"score_spread":0.2041794818928543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}