{"id":"W3110033516","doi":"10.1016/j.csbj.2020.11.034","title":"Loss of Arp1, a putative actin-related protein, triggers filamentous and invasive growth and impairs pathogenicity in <i>Candida albicans</i>","year":2020,"lang":"en","type":"article","venue":"Computational and Structural Biotechnology Journal","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Candida albicans; Virulence; Biology; Corpus albicans; Cell biology; Microbiology; Fungal protein; Saccharomyces cerevisiae; Yeast; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009410236,0.0003789302,0.0001908785,0.0003378211,0.0002488706,0.00057152,0.0003833402,0.0003625935,0.001984283],"category_scores_gemma":[0.000164985,0.0001612565,0.0002743537,0.0002279792,0.000210516,0.0001340037,0.0002141992,0.0007977818,0.0006591156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004008758,"about_ca_system_score_gemma":0.0003199272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003071405,"about_ca_topic_score_gemma":0.003130814,"domain_scores_codex":[0.9998259,0.00002091244,0.00001701509,0.00003201644,0.00006231905,0.0000418649],"domain_scores_gemma":[0.9998769,0.0000182354,0.00003733972,0.00001552683,0.00001192041,0.0000400914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003795372,0.00007076991,0.0003434455,0.00004021905,0.0000132706,0.0001468816,0.0000103959,0.0002387362,0.9958567,0.0002157559,0.0004897663,0.002194541],"study_design_scores_gemma":[0.00003707204,0.0002569859,0.01009504,0.00002101123,0.00003093665,0.0006273883,0.00007391891,0.004628066,0.9800925,0.0001722304,0.003946787,0.00001803284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900748,0.0007815016,0.001965626,0.0002468349,0.0001004642,0.00003075236,0.002328123,0.0003133087,0.004158473],"genre_scores_gemma":[0.9936986,0.0004539582,0.001501314,0.0001127931,0.00001143153,0.00001970216,0.001564595,0.00006873111,0.002568806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003071405,"threshold_uncertainty_score":0.00663805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009184406540918193,"score_gpt":0.2391558911016641,"score_spread":0.2299714845607459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}