{"id":"W3110058912","doi":"10.1002/advs.202001596","title":"The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD‐L1","year":2020,"lang":"en","type":"article","venue":"Advanced Science","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Overseas Expertise Introduction Project for Discipline Innovation; China Postdoctoral Science Foundation; Natural Science Foundation of Shanghai","keywords":"Sunitinib; Immune system; Cancer research; Immune checkpoint; Medicine; In vivo; Cancer; Antibody; Immunotherapy; Monoclonal antibody; Cytotoxic T cell; Immunology; In vitro; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006588554,0.0001111205,0.000231388,0.00004454983,0.0002120956,0.00002226159,0.0003382355,0.00001578652,0.00002134726],"category_scores_gemma":[0.0004940872,0.00008176477,0.00005625105,0.001172571,0.000620075,0.0001645426,0.00006535418,0.0001422566,0.000002716148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006697167,"about_ca_system_score_gemma":0.0002072462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000117943,"about_ca_topic_score_gemma":0.00005329597,"domain_scores_codex":[0.9985401,0.00003104189,0.0003852647,0.0002929172,0.0004049716,0.0003456855],"domain_scores_gemma":[0.9992054,0.0001520659,0.0001879194,0.0002649753,0.000107988,0.0000816317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001017537,0.00002494967,0.00431663,0.00001634644,0.000004232865,0.000003912058,0.0004935701,0.00008011057,0.9592215,0.0001097741,0.00002199119,0.03468939],"study_design_scores_gemma":[0.00366889,0.0007232655,0.1428171,0.0002258573,0.00000754174,0.00003272357,0.004398952,0.004885698,0.8233832,0.0002043362,0.01932088,0.0003315722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939816,0.002992629,0.00002694094,0.001475481,0.0001087264,0.0002597508,0.00001293943,0.00002750168,0.001114433],"genre_scores_gemma":[0.9987612,0.00009060334,0.0004995192,0.0005460604,0.00003960092,0.000008512218,0.000003037765,0.00001029103,0.00004116614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1385004,"threshold_uncertainty_score":0.3334271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00954921457374333,"score_gpt":0.2636963244491223,"score_spread":0.254147109875379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}