{"id":"W3110094893","doi":"10.2139/ssrn.3726142","title":"<i>Prunella vulgaris</i> Extract Blocks SARS- <i>Coronavirus 2</i> Virus Spike Protein D614 and G614 Variants Mediated Receptor Binding and Virus Entry","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"","keywords":"Virology; Suramin; Virus; Infectivity; Biology; Vero cell; Viral entry; Coronavirus; Receptor; Viral replication; Medicine; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.002559225,0.001200547,0.001427702,0.0004722704,0.001527314,0.0002528813,0.001045522,0.001397518,0.001698331],"category_scores_gemma":[0.000520503,0.00115964,0.0003959277,0.000626641,0.0005421035,0.0006812604,0.0004957091,0.004816073,0.001027299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008095565,"about_ca_system_score_gemma":0.001840144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005563946,"about_ca_topic_score_gemma":0.0008625049,"domain_scores_codex":[0.9906368,0.0009595587,0.001605656,0.001479537,0.0004094808,0.004908978],"domain_scores_gemma":[0.9973369,0.0002904417,0.001068889,0.0006651403,0.0002110659,0.0004275346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001278879,0.0003839049,0.0001099676,0.00004134756,0.001250775,0.00008026692,0.0007341686,0.000004619744,0.9660894,0.008607388,0.001364373,0.02005487],"study_design_scores_gemma":[0.01680963,0.006713927,0.003139283,0.0005759234,0.0009640537,0.004498701,0.0006001393,0.0002057044,0.5463459,0.007308213,0.4092896,0.003548866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9166121,0.0766714,0.00167599,0.000979064,0.001414082,0.001309329,0.0003296761,0.0002745388,0.0007338572],"genre_scores_gemma":[0.9546887,0.03836758,0.0004137316,0.0004970595,0.0005701747,0.0000789986,0.0002284623,0.0002345778,0.004920659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4197435,"threshold_uncertainty_score":0.9998989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194745949217122,"score_gpt":0.2265699929396395,"score_spread":0.2146225334474683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}