{"id":"W3110098604","doi":"10.1080/14760584.2020.1857736","title":"B cell targeting by molecular adjuvants for enhanced immunogenicity","year":2020,"lang":"en","type":"review","venue":"Expert Review of Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Adjuvant; Immune system; Immunogenicity; Antigen; Immunology; Biology; Receptor; B-cell activating factor; Antibody; B cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005055254,0.0008488037,0.00456853,0.0001042863,0.0001516207,0.0000128818,0.001011734,0.000555117,0.0009084029],"category_scores_gemma":[0.0005806791,0.000638932,0.001995865,0.0003338257,0.00006833106,0.00008755039,0.0001764972,0.0004433677,0.0002316939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005924522,"about_ca_system_score_gemma":0.0002925025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001934101,"about_ca_topic_score_gemma":8.838615e-8,"domain_scores_codex":[0.995958,0.000853365,0.001901016,0.0006741319,0.00006785456,0.0005456731],"domain_scores_gemma":[0.9970834,0.0005699282,0.001387148,0.0007285247,0.0002006331,0.00003041762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001024622,0.0001128306,2.572036e-8,0.07539194,0.0006670913,0.000001536516,0.00006183155,7.106846e-9,0.1531704,0.000007371334,0.1101882,0.6602963],"study_design_scores_gemma":[0.0006225096,0.0002231007,3.398614e-8,0.05436106,0.0004653012,0.00001908747,0.0000150282,3.689198e-8,0.1342309,0.000002128909,0.8095659,0.0004949592],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000004137993,0.99525,0.0005313244,0.0001299899,0.001050352,0.002565823,0.000261912,0.00007114919,0.0001353541],"genre_scores_gemma":[0.000006152375,0.9954328,0.0004064591,0.0006510471,0.0000829975,0.0007002606,0.001518481,0.0001321459,0.001069632],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6993777,"threshold_uncertainty_score":0.9996062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01493597508836858,"score_gpt":0.3253977072829739,"score_spread":0.3104617321946053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}