{"id":"W3110157031","doi":"10.3389/fmolb.2020.582660","title":"Alteration of Membrane Fluidity or Phospholipid Composition Perturbs Rotation of MreB Complexes in Escherichia coli","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Biosciences","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"MreB; Peptidoglycan; Lipid II; Cardiolipin; Transmembrane protein; Biophysics; Cell biology; Membrane; Phospholipid; Biology; Cell wall; Membrane fluidity; Escherichia coli; Cell envelope; Cytoplasm; Biochemistry; Cell membrane; Chemistry; Cell; Cytoskeleton","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001606425,0.0001138706,0.0002245805,0.0000900763,0.00002361977,0.00001247071,0.0002483249,0.0001585688,0.000005336604],"category_scores_gemma":[0.00007571685,0.0001017567,0.00004620796,0.0004432616,0.0002735911,0.000007542434,0.00007090143,0.00006685661,2.547205e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001112151,"about_ca_system_score_gemma":0.00007821012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006033719,"about_ca_topic_score_gemma":0.0000314742,"domain_scores_codex":[0.998965,0.00009020836,0.0003346781,0.0003075681,0.000147389,0.0001551727],"domain_scores_gemma":[0.9996155,0.000004615276,0.0001458283,0.0001384812,0.00005645216,0.00003916117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002023526,0.00006777963,0.004515707,0.00004216994,0.000007960514,0.000001967026,0.0001031558,0.000365448,0.9940194,0.00004805172,0.00009447383,0.0005315705],"study_design_scores_gemma":[0.0004723303,0.0005618826,0.005849994,0.00002332589,0.000006277035,9.060905e-7,0.0001486928,0.003668292,0.9887877,0.0000478481,0.0003159154,0.0001168709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846965,0.000442781,0.01383144,0.0004760979,0.0002659012,0.0002327847,0.0000190261,0.000004717362,0.00003075843],"genre_scores_gemma":[0.9810081,0.0002522981,0.01838322,0.000249862,0.00002957993,0.000007742034,0.00005976634,0.000006584981,0.00000290138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005231699,"threshold_uncertainty_score":0.4149519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01091753602554227,"score_gpt":0.2310826140009744,"score_spread":0.2201650779754321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}