{"id":"W3110193010","doi":"10.1016/j.bpj.2020.10.046","title":"Protection or Destruction: The LL-37/HNP1 Cooperativity Switch","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cooperativity; Biophysics; Chemistry; Cell biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004193892,0.0003522354,0.0003443586,0.0001029199,0.000322038,0.0005725209,0.000494986,0.0004713801,0.003449861],"category_scores_gemma":[0.0005716104,0.0001791253,0.0002010298,0.00008067162,0.0007195107,0.0007040359,0.0007360721,0.0007805557,0.001013052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000623494,"about_ca_system_score_gemma":0.00035129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005805246,"about_ca_topic_score_gemma":0.0004515118,"domain_scores_codex":[0.9997746,0.00002195553,0.000009004957,0.00005549801,0.00005008194,0.00008884125],"domain_scores_gemma":[0.9996574,0.00008808426,0.00004719588,0.00006978266,0.00003257275,0.0001049922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003067606,0.00003512404,0.0006543277,0.00003812155,0.000004881275,0.0001780092,0.00005350855,0.0002516344,0.993401,0.001403786,0.000387764,0.003285102],"study_design_scores_gemma":[0.00002703343,0.00008824388,0.00408413,0.000009008475,0.000008477002,0.0003064038,0.00009977015,0.004721583,0.9861016,0.001374435,0.003163546,0.00001571541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866998,0.001202666,0.005346913,0.0008042931,0.0001142912,0.00001885277,0.0001190853,0.0003178699,0.005376278],"genre_scores_gemma":[0.9974943,0.0001769692,0.0005724858,0.0001163711,0.0000136582,0.000007278177,0.00008349474,0.0000296566,0.001505591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003449861,"threshold_uncertainty_score":0.01154095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03684028908658687,"score_gpt":0.2758200824078318,"score_spread":0.238979793321245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}