{"id":"W3110292664","doi":"","title":"11th GPCR Retreat (Canada) - A deletion approach highlights unexpected subtype-specific roles of the third intracellular loop of D1-like dopaminergic receptors: revisiting the extended ternary complex model","year":2010,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein-coupled receptor; Dopaminergic; Receptor; Intracellular; Ternary complex; Neuroscience; Biology; Computational biology; Cell biology; Genetics; Dopamine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003375994,0.0004543531,0.0006115603,0.0003266232,0.0008829533,0.001162468,0.001456702,0.0008696077,0.003550717],"category_scores_gemma":[0.0003737662,0.0002493718,0.0006388942,0.000232003,0.001138826,0.0009086857,0.00073557,0.002135959,0.001194934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002280895,"about_ca_system_score_gemma":0.001881677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01494942,"about_ca_topic_score_gemma":0.01895944,"domain_scores_codex":[0.9996636,0.00003155664,0.00002808639,0.00009364245,0.0001100485,0.0000730739],"domain_scores_gemma":[0.9997742,0.00005954247,0.00004206065,0.00004531424,0.00003567395,0.00004333385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003027307,0.00005993969,0.0002784316,0.000083406,0.00001347966,0.0005385854,0.0001000689,0.001169631,0.9682412,0.0211789,0.000780582,0.007253049],"study_design_scores_gemma":[0.00007741035,0.0001311045,0.001520375,0.0000261268,0.00006151947,0.001449412,0.0001542579,0.01806419,0.9441955,0.005012073,0.02923353,0.0000743798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8866272,0.002118262,0.08192468,0.003192159,0.0004040833,0.0001636111,0.001466191,0.000705984,0.02339773],"genre_scores_gemma":[0.9585699,0.001266057,0.02678709,0.0006922476,0.00003296492,0.00007798023,0.0007237807,0.0002342312,0.01161582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01494942,"threshold_uncertainty_score":0.02972478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01169210440312131,"score_gpt":0.2026150744211024,"score_spread":0.1909229700179811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}