{"id":"W3110443107","doi":"10.1038/s41598-020-77565-2","title":"Conserved epitopes with high HLA-I population coverage are targets of CD8+ T cells associated with high IFN-γ responses against all dengue virus serotypes","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council; National Institutes of Health","keywords":"Virology; Epitope; Serotype; Dengue virus; Dengue fever; Biology; Population; Human leukocyte antigen; Virus; CD8; Immunology; Antibody; Antigen; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009553692,0.0001567954,0.0001405111,0.0001597772,0.0001175812,0.000272055,0.00008445844,0.0001593001,0.001914154],"category_scores_gemma":[0.0001410086,0.00008681863,0.0001290001,0.0001653943,0.0001611729,0.0001161114,0.000172405,0.000215856,0.0002664924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000959462,"about_ca_system_score_gemma":0.00009059293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004146379,"about_ca_topic_score_gemma":0.0003482463,"domain_scores_codex":[0.9999087,0.00001501297,0.000005730653,0.00003236219,0.00001697069,0.00002125503],"domain_scores_gemma":[0.9999082,0.00001659089,0.00003723879,0.00001116228,0.00001368274,0.00001309926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001769948,0.00003507692,0.04891486,0.00006015033,0.00002907002,0.000108154,0.00006682685,0.000348051,0.9452578,0.00008723839,0.00005324731,0.004862525],"study_design_scores_gemma":[0.00002690662,0.0004649657,0.6589958,0.00002447951,0.00009963234,0.002265074,0.0006004067,0.002897952,0.3312798,0.0004342409,0.002901037,0.000009726436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998368,0.0001528494,0.0008387903,0.000008748634,0.000001810474,0.000003513162,0.0001086453,0.000006929365,0.000510649],"genre_scores_gemma":[0.9992735,0.00005190761,0.0003945616,0.000008940729,0.000001037558,0.000002524336,0.0001322421,0.000001926883,0.0001333905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001914154,"threshold_uncertainty_score":0.006403446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451496219449945,"score_gpt":0.2321158678054368,"score_spread":0.2176009056109373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}