{"id":"W3110575363","doi":"10.1158/2643-3249.lymphoma20-po-26","title":"Abstract PO-26: Prognostic significance of Fc gamma receptor IIB expression in the response of previously untreated diffuse large B-cell lymphomas to anti-CD20 monoclonal antibodies: Differing impact of rituximab and obinutuzumab","year":2020,"lang":"en","type":"article","venue":"Blood Cancer Discovery","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Spinal Cord Injury BC","funders":"","keywords":"Rituximab; International Prognostic Index; CHOP; CD20; Tissue microarray; Immunohistochemistry; Lymphoma; Medicine; Diffuse large B-cell lymphoma; Monoclonal antibody; Cancer research; Internal medicine; Oncology; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004210075,0.0003502825,0.0009602915,0.0001764864,0.00006309519,0.00003115898,0.000320921,0.0001151538,0.0000867476],"category_scores_gemma":[0.0003343961,0.0002260035,0.0002634072,0.0005344664,0.0002160052,0.0001982749,0.0001925219,0.0002696005,0.000004023112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000114304,"about_ca_system_score_gemma":0.0007856484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515113,"about_ca_topic_score_gemma":0.00005525076,"domain_scores_codex":[0.9972785,0.000232711,0.0007555187,0.0004999065,0.0006907112,0.0005426936],"domain_scores_gemma":[0.9982481,0.0006660646,0.0003222787,0.0003710103,0.000146428,0.0002461245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01740258,0.002328642,0.3101683,0.001755614,0.0001697338,0.00007920618,0.003225973,0.0000722163,0.664195,0.000005822054,0.000301339,0.0002955427],"study_design_scores_gemma":[0.01029958,0.002373261,0.6426589,0.001643459,0.0001494089,0.00001428749,0.0005432828,0.0001197426,0.3418474,0.000006167703,0.0001116206,0.0002327662],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927668,0.004269769,0.00001443328,0.0005207814,0.00003592254,0.001285555,0.00101186,0.00002045357,0.00007441227],"genre_scores_gemma":[0.997385,0.00196333,0.0001692227,0.0001113074,0.00009792402,0.00008380163,0.00004055367,0.00004555002,0.0001033447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3324907,"threshold_uncertainty_score":0.9216155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02231961598826306,"score_gpt":0.3019578942477443,"score_spread":0.2796382782594812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}