{"id":"W3110677243","doi":"10.1002/slct.202003893","title":"Influence of C5‐Substituents on Repair of O 4 ‐Methyl Adducts of Pyrimidines by O 6 ‐Alkylguanine DNA Alkyltransferases","year":2020,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Trifluoromethyl; Adduct; DNA; Chemistry; Halogen; Alkylation; Stereochemistry; Nucleobase; DNA repair; Deoxyguanosine; Thymidine; Medicinal chemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002715246,0.0003533608,0.0002221152,0.0001411485,0.0001363181,0.0002074493,0.0003109975,0.0002694732,0.001628843],"category_scores_gemma":[0.000745078,0.0001348261,0.0001730042,0.0001428306,0.0001636525,0.0001846648,0.0001451947,0.0002405004,0.0003399544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000156045,"about_ca_system_score_gemma":0.0001907606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001015784,"about_ca_topic_score_gemma":0.0007936985,"domain_scores_codex":[0.999768,0.00007442316,0.00001722572,0.00004382215,0.00004574892,0.00005072475],"domain_scores_gemma":[0.9994189,0.0002522707,0.0001380275,0.00003606282,0.00009192828,0.00006280399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006583894,0.00002861241,0.0004832311,0.00009980524,0.00002311127,0.00005873227,0.00004345821,0.000421817,0.9962307,0.00004405082,0.00003709688,0.00187095],"study_design_scores_gemma":[0.000007668767,0.0006786198,0.001425818,0.000008724979,0.00002710272,0.00004080182,0.00002417352,0.0004537111,0.9965995,0.00001017966,0.0007164991,0.000007211689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982544,0.0005314026,0.0004252557,0.00001628772,0.00001108309,0.000008108009,0.00008202054,0.00001612332,0.0006553116],"genre_scores_gemma":[0.9985847,0.0002597342,0.0005375246,0.00002298383,0.000004176986,0.000006708806,0.0001472808,0.00001676948,0.0004200807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001628843,"threshold_uncertainty_score":0.005449057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007936069888716238,"score_gpt":0.2171474424296639,"score_spread":0.2092113725409477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}