{"id":"W3110718005","doi":"10.1101/2020.12.13.422535","title":"Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Hippocampal formation; Endocrinology; Internal medicine; Choline acetyltransferase; Hippocampus; Biology; Acetylcholinesterase; Dentate gyrus; NeuN; Acetylcholine; Medicine; Biochemistry; Enzyme; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003003668,0.0007092665,0.0005205158,0.001947146,0.0003757712,0.0005947491,0.0004829004,0.0009156879,0.003793493],"category_scores_gemma":[0.0001949133,0.0005450306,0.0005410856,0.0004057318,0.0006507121,0.000461363,0.0003787119,0.001096045,0.000720984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005230707,"about_ca_system_score_gemma":0.0003071501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00187286,"about_ca_topic_score_gemma":0.003007913,"domain_scores_codex":[0.9994965,0.00004501011,0.00005051418,0.0001891811,0.0001040459,0.0001147981],"domain_scores_gemma":[0.9994431,0.00002555154,0.0002581224,0.00004062674,0.0000579637,0.000174661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00138486,0.0002178741,0.002653625,0.00006812802,0.00002844045,0.000235713,0.00009778442,0.00003042437,0.9924214,0.0000993318,0.000144727,0.00261765],"study_design_scores_gemma":[0.0002824239,0.003316777,0.1383411,0.0000980348,0.0002787861,0.002186419,0.000674442,0.0007300855,0.8472871,0.0003481829,0.006381161,0.00007555009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919384,0.001836078,0.001508638,0.0002420925,0.00005658473,0.00004124781,0.002790333,0.0001635061,0.001423079],"genre_scores_gemma":[0.9775426,0.001952485,0.002998743,0.0002869137,0.00002847123,0.000218257,0.001795821,0.0001624014,0.01501429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003793493,"threshold_uncertainty_score":0.01269054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02610257570438308,"score_gpt":0.2748892811405778,"score_spread":0.2487867054361947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}