{"id":"W3110853086","doi":"10.1016/j.isci.2020.101943","title":"CCL22 induces pro-inflammatory changes in fibroblast-like synoviocytes","year":2020,"lang":"en","type":"article","venue":"iScience","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CCL22; Chemokine; Cancer research; CCR3; Chemistry; Gene knockdown; CCR4; CCL11; Immunology; Chemokine receptor; Inflammation; Cell biology; Apoptosis; Molecular biology; Biology; Eotaxin; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417527,0.0004668803,0.0002901072,0.0003501314,0.0002074236,0.0003394547,0.00007213633,0.0002865583,0.001317659],"category_scores_gemma":[0.0001518444,0.0001059061,0.0002887388,0.0001714638,0.0001695496,0.0001914132,0.0001834818,0.0003907918,0.0003296586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001814577,"about_ca_system_score_gemma":0.0002134862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006071381,"about_ca_topic_score_gemma":0.001343347,"domain_scores_codex":[0.999714,0.00006990278,0.00003076671,0.00003696821,0.00006466701,0.00008372923],"domain_scores_gemma":[0.999858,0.00001761464,0.00003477868,0.00001580949,0.00002928745,0.0000443922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000856058,0.00002937053,0.000347739,0.00006483142,0.000005395264,0.00009839074,0.0000163433,0.00001718879,0.9982597,0.0000256753,0.00003297258,0.001016762],"study_design_scores_gemma":[0.00005032766,0.001513872,0.03079298,0.00002662801,0.00004368058,0.0008790917,0.0001524294,0.0007091177,0.960935,0.00008553417,0.004797982,0.00001338407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884928,0.007522064,0.001672351,0.0001291475,0.00005263309,0.00004685657,0.0003057828,0.00006591025,0.001712388],"genre_scores_gemma":[0.9945552,0.002094873,0.001157645,0.0001418131,0.00003516183,0.00005496164,0.0003222057,0.00000850548,0.001629513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001317659,"threshold_uncertainty_score":0.004408002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03265579364113767,"score_gpt":0.2684466693098057,"score_spread":0.235790875668668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}