{"id":"W3110910606","doi":"10.1093/neuonc/noaa222.222","title":"ETMR-19. SINGLE CELL ANALYSES OF ETMRs REVEAL THAT C19MC+ POPULATION DRIVES CELL CYCLE PROGRESSION AND STEM CELL MAINTENANCE","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Stem cell; Population; Wnt signaling pathway; Biology; Cell; Cell cycle; Cell biology; Cancer research; Cell growth; Signal transduction; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002167988,0.0002172843,0.0002121075,0.0003008876,0.0003615894,0.0003579804,0.0002110959,0.0002597071,0.003929921],"category_scores_gemma":[0.0001861061,0.0001462647,0.0002809311,0.0002686759,0.0002019208,0.000164296,0.0002732013,0.0005672105,0.001439665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003563401,"about_ca_system_score_gemma":0.000195131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002280426,"about_ca_topic_score_gemma":0.004171439,"domain_scores_codex":[0.9997985,0.00001032163,0.00001486391,0.00008422912,0.00006016215,0.00003188065],"domain_scores_gemma":[0.9998025,0.00003641705,0.0000373854,0.00003542733,0.00003908254,0.00004917777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005408466,0.000008504804,0.00103194,0.00002105423,0.000006065492,0.00004823334,0.00002825633,0.00006314398,0.997102,0.0001456738,0.0001814186,0.001309555],"study_design_scores_gemma":[0.000009164753,0.0001155269,0.03118098,0.000006371493,0.00001467477,0.0003807867,0.00004943761,0.002036381,0.956694,0.0001237754,0.009379106,0.000009679567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507101,0.000875921,0.02196736,0.0001445555,0.00005948279,0.0001223947,0.01980747,0.0006831286,0.00562951],"genre_scores_gemma":[0.9407253,0.000492086,0.02234943,0.0001905958,0.00001485103,0.00021616,0.02174179,0.0003533826,0.01391647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003929921,"threshold_uncertainty_score":0.01314688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02880401515716268,"score_gpt":0.3000608368424066,"score_spread":0.271256821685244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}