{"id":"W3110946494","doi":"10.14309/01.ajg.0000722920.48091.e7","title":"P031 Ozanimod in Patients with Moderate-to-Severe Ulcerative Colitis: Long-Term Safety and Efficacy from the Phase 2 TOUCHSTONE Study 4-Year Open-Label Extension","year":2020,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Western University","funders":"","keywords":"Medicine; Ulcerative colitis; Internal medicine; Calprotectin; Placebo; Gastroenterology; Surgery; Inflammatory bowel disease; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002251045,0.0005977283,0.001409996,0.0002667145,0.0002754852,0.000769272,0.0004934469,0.0008011677,0.003751359],"category_scores_gemma":[0.001273807,0.0003144332,0.00134436,0.0003849524,0.0003896466,0.0007808488,0.0005068961,0.001583846,0.0006518625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003440055,"about_ca_system_score_gemma":0.0007783459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002477466,"about_ca_topic_score_gemma":0.0008813671,"domain_scores_codex":[0.9994443,0.000257124,0.00004883823,0.00008516897,0.00008301818,0.00008155716],"domain_scores_gemma":[0.9990263,0.0001752988,0.0003206508,0.00009697031,0.00009215668,0.0002886285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8018976,0.01872877,0.01587711,0.00168093,0.002255482,0.0002764236,0.0002128113,0.0009162552,0.01979946,0.0001515379,0.003641002,0.1345626],"study_design_scores_gemma":[0.4583282,0.4480824,0.0813062,0.0001801611,0.001727003,0.000458244,0.0001156719,0.000916728,0.002309309,0.0001956209,0.006329234,0.00005120183],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990415,0.005197919,0.0004247709,0.0003057811,0.0000705728,0.001027833,0.001055173,0.00007183519,0.001431125],"genre_scores_gemma":[0.9899462,0.002709806,0.0009236842,0.0008158266,0.00013723,0.001126149,0.00261957,0.0000162081,0.001705314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003751359,"threshold_uncertainty_score":0.01254958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01212626950585285,"score_gpt":0.2704067039845261,"score_spread":0.2582804344786733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}