{"id":"W3111053993","doi":"10.1016/j.cell.2020.10.046","title":"Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria","year":2020,"lang":"en","type":"article","venue":"Cell","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Genomics; BC Children's Hospital; University of British Columbia; McGill University; McGill Genome Centre","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche","keywords":"Biology; Innate immune system; Immunology; Acquired immune system; Interferon gamma; CD8; Immunity; Interferon; Antigen; T lymphocyte; Cytokine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003116178,0.0002723768,0.0002430374,0.000221466,0.0002414758,0.0007563662,0.0002273551,0.0004252864,0.001751118],"category_scores_gemma":[0.0003613874,0.0001778392,0.0001622658,0.0001254087,0.000273623,0.0003829944,0.0002631543,0.0006710697,0.0006289593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002335485,"about_ca_system_score_gemma":0.0001726443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001955602,"about_ca_topic_score_gemma":0.0003594117,"domain_scores_codex":[0.9996927,0.00007305422,0.00002005113,0.00005434881,0.0000492468,0.000110659],"domain_scores_gemma":[0.9998531,0.00003789835,0.00002794033,0.00002285328,0.00001887115,0.00003935756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000649955,0.00004710394,0.004408902,0.00003499253,0.0000101778,0.0001190625,0.00005735849,0.000164213,0.9894059,0.0004632241,0.0001471714,0.004491859],"study_design_scores_gemma":[0.0001555515,0.001001938,0.07634566,0.00004191294,0.00008867969,0.002568408,0.0006177668,0.005854063,0.9042419,0.001882172,0.007178607,0.00002335046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965315,0.0008808897,0.0006517571,0.00005857635,0.00002322822,0.00001220572,0.0001099155,0.00002516471,0.001706627],"genre_scores_gemma":[0.9986057,0.0001686802,0.000257305,0.00004653061,0.00001623916,0.00000746991,0.0001620714,0.00001085604,0.0007251705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001751118,"threshold_uncertainty_score":0.005858123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01844179411182043,"score_gpt":0.2218970142548794,"score_spread":0.203455220143059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}