{"id":"W3111064764","doi":"10.1186/s12864-020-07186-6","title":"Cell-specific characterization of the placental methylome","year":2021,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Hospital for Sick Children; BC Children's Hospital","keywords":"dNaM; Biology; DNA methylation; Population; Placenta; Methylation; Trophoblast; Epigenetics; Cell type; Bioinformatics; Cell; Fetus; Pregnancy; Genetics; Gene; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008494207,0.00006494053,0.00006802182,0.00001036814,0.00004179156,0.00001140322,0.0001001497,0.00007390582,0.0000176782],"category_scores_gemma":[0.00001602156,0.00005671398,0.00007353045,0.00006493879,0.00002544204,0.00000115826,0.0000966914,0.00003420212,0.000004312492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000120444,"about_ca_system_score_gemma":0.00009377723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001233357,"about_ca_topic_score_gemma":0.000006513583,"domain_scores_codex":[0.9994787,0.00005738606,0.000154696,0.0001561399,0.00006721148,0.00008584502],"domain_scores_gemma":[0.999526,0.000006289513,0.00009024233,0.0002883566,0.00006602192,0.00002304402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001094935,0.00002817394,0.004791039,0.000009590348,0.000004966425,1.42041e-7,0.0000405928,0.0001049187,0.9946058,0.00004808541,0.00004523704,0.0003105091],"study_design_scores_gemma":[0.0001776305,0.00001792327,0.0268658,0.000001972743,0.000006021419,8.40048e-7,0.00003755687,0.0000312956,0.9348061,0.00004169698,0.03794995,0.00006321482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913903,0.001627479,0.005971482,0.00002722427,0.0002611827,0.00007999424,0.00003155728,0.000002085448,0.0006086687],"genre_scores_gemma":[0.9965816,0.0007320593,0.001491031,0.00003415461,0.0001307438,0.000002912036,0.0002005612,0.00001338077,0.00081357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05979969,"threshold_uncertainty_score":0.2312729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360668218075058,"score_gpt":0.2181083556331623,"score_spread":0.2045016734524117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}