{"id":"W3111064764","doi":"10.1186/s12864-020-07186-6","title":"Cell-specific characterization of the placental methylome","year":2021,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Hospital for Sick Children; BC Children's Hospital","keywords":"dNaM; Biology; DNA methylation; Population; Placenta; Methylation; Trophoblast; Epigenetics; Cell type; Bioinformatics; Cell; Fetus; Pregnancy; Genetics; Gene; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002619487,0.000168546,0.0002367456,0.0007554387,0.0002272593,0.0004526758,0.0002064796,0.0002451228,0.002076479],"category_scores_gemma":[0.0006308814,0.0001382843,0.0002466661,0.0005765639,0.0001955335,0.0001636408,0.0004760721,0.0004943574,0.0005877659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002335463,"about_ca_system_score_gemma":0.0002742522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002038023,"about_ca_topic_score_gemma":0.002841472,"domain_scores_codex":[0.9998399,0.00001534811,0.000007315545,0.00006553601,0.00004582692,0.00002617387],"domain_scores_gemma":[0.9997875,0.00006003104,0.00003576214,0.00003576143,0.00005180095,0.00002914298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002103351,0.00001052777,0.0463243,0.0002664058,0.00008605063,0.0001881457,0.0003277452,0.0003325682,0.9264882,0.0003846615,0.0006567181,0.02472441],"study_design_scores_gemma":[0.00002824926,0.000209174,0.4354642,0.00009085119,0.0002015382,0.002311366,0.0004322768,0.003345054,0.517436,0.001172676,0.03927153,0.00003713533],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9239364,0.008542431,0.04300532,0.0003572006,0.00006064004,0.0001058864,0.01741878,0.0004075871,0.006165599],"genre_scores_gemma":[0.9698564,0.003050461,0.01584685,0.0001772385,0.00003087155,0.0001597035,0.00853918,0.0001169051,0.002222364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002076479,"threshold_uncertainty_score":0.006946504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360668218075058,"score_gpt":0.2181083556331623,"score_spread":0.2045016734524117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}