{"id":"W3111229185","doi":"10.1093/neuonc/noaa222.405","title":"LGG-23. EXCELLENT CLINICAL / RADIOLOGICAL RESPONSE TO BRAF INHIBITION IN A YOUNG CHILD WITH IN-OPERABLE SUPRA-SELLAR PILOCYTIC ASTROCYTOMA","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Medicine; Trametinib; Pilocytic astrocytoma; Temozolomide; Oncology; Regimen; Internal medicine; Population; Lomustine; Vincristine; Dabrafenib; Chemotherapy; Vemurafenib; Glioma; Radiology; Astrocytoma; Cancer research; Cancer; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000872368,0.0005868509,0.0005063096,0.0005297962,0.0008671833,0.0004401304,0.000339948,0.001160067,0.0010943],"category_scores_gemma":[0.0005442366,0.0002235877,0.0004126834,0.000310953,0.0004860061,0.0004642632,0.000328656,0.001378693,0.0003657573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001039437,"about_ca_system_score_gemma":0.0005859717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004568462,"about_ca_topic_score_gemma":0.00869934,"domain_scores_codex":[0.9999028,0.000008145646,0.000009088962,0.00002666304,0.00001534861,0.00003795137],"domain_scores_gemma":[0.9997122,0.00003675968,0.00005359162,0.000008496635,0.00002660903,0.0001622913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0000720742,0.00005857776,0.02438164,0.00004825087,0.000009762791,0.969799,0.0001403824,0.00008348333,0.002410215,0.0001034572,0.0005360686,0.002357147],"study_design_scores_gemma":[0.00001077392,0.000437202,0.0443589,0.00003393684,0.00002248168,0.9514955,0.000224143,0.0002651561,0.001173664,0.0001460932,0.001817101,0.00001511317],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846798,0.003522724,0.0007304886,0.003439429,0.0001552025,0.0001143055,0.0006287859,0.000133417,0.006595885],"genre_scores_gemma":[0.9970047,0.0008518902,0.0003958842,0.0005917595,0.00006378213,0.00001374555,0.0001729144,0.00001781253,0.0008874767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004568462,"threshold_uncertainty_score":0.009083748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03698386997312395,"score_gpt":0.3199909218274263,"score_spread":0.2830070518543024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}