{"id":"W3111413536","doi":"10.1242/dev.194480","title":"Satellite cell expansion is mediated by P-eIF2α dependent <i>Tacc3</i> translation","year":2020,"lang":"en","type":"article","venue":"Development","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Uehara Memorial Foundation; Canadian Institutes of Health Research; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Ministry of Education, Culture, Sports, Science and Technology; Stem Cell Network","keywords":"Biology; Cell biology; Translation (biology); Eukaryotic translation; Satellite; Integrated stress response; Mitosis; Translational regulation; Messenger RNA; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005696322,0.0001359995,0.0001006315,0.00001243615,0.000059937,0.000007788006,0.0001126089,0.0001309922,0.00009024306],"category_scores_gemma":[0.000008937345,0.0001328771,0.0000371066,0.00005978529,0.00002059776,0.00000347213,0.00004003699,0.00006370839,0.0001104817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006753778,"about_ca_system_score_gemma":0.00008719639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003567192,"about_ca_topic_score_gemma":0.000005879727,"domain_scores_codex":[0.9991527,0.00003219416,0.0001900738,0.0003264141,0.0001171592,0.000181496],"domain_scores_gemma":[0.9996998,0.00000689647,0.0000482691,0.0001117993,0.00002671796,0.0001064876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001313474,0.00005350883,0.0005981462,0.00002147565,0.0000221636,0.000001016127,0.0009066178,0.00000918516,0.9691933,0.000001271838,0.01005859,0.01900334],"study_design_scores_gemma":[0.0005704139,0.0000614127,0.00163178,0.0000027208,0.000004903936,3.312859e-7,0.0000645995,0.00001875029,0.7163565,0.000009759253,0.2811124,0.0001664118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912246,0.002671024,0.002295314,0.00125789,0.00008748953,0.0002058919,0.00002537979,0.00002834174,0.002204094],"genre_scores_gemma":[0.9919234,0.000635652,0.0007873116,0.005303227,0.0000379292,0.00002033104,0.001119784,0.00001524229,0.0001571552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2710539,"threshold_uncertainty_score":0.5418569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286691419493592,"score_gpt":0.2119522021777075,"score_spread":0.1990852879827715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}