{"id":"W3111413536","doi":"10.1242/dev.194480","title":"Satellite cell expansion is mediated by P-eIF2α dependent <i>Tacc3</i> translation","year":2020,"lang":"en","type":"article","venue":"Development","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Uehara Memorial Foundation; Canadian Institutes of Health Research; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Ministry of Education, Culture, Sports, Science and Technology; Stem Cell Network","keywords":"Biology; Cell biology; Translation (biology); Eukaryotic translation; Satellite; Integrated stress response; Mitosis; Translational regulation; Messenger RNA; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008499669,0.0002695737,0.0002179461,0.0001731085,0.0001800332,0.0002496961,0.0001120177,0.0001568123,0.000813969],"category_scores_gemma":[0.00008008601,0.0001002502,0.000285089,0.0001544002,0.0002224113,0.0001160107,0.0001922768,0.0003492776,0.0003360808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551117,"about_ca_system_score_gemma":0.0001881084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007211761,"about_ca_topic_score_gemma":0.001172311,"domain_scores_codex":[0.9999142,0.000006441929,0.000006365979,0.00002024613,0.00003272995,0.00001998486],"domain_scores_gemma":[0.9999037,0.00001418684,0.0000334498,0.00001064574,0.00001435656,0.00002371787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001673303,0.000002431882,0.00008481293,0.000009870692,8.040823e-7,0.0000182604,0.00000305634,0.000007214814,0.9996038,0.00001407116,0.00001421864,0.0002247502],"study_design_scores_gemma":[0.000007354754,0.0001200606,0.02576818,0.00000827119,0.000008838886,0.0002646946,0.00002460558,0.0005676745,0.971067,0.00003407871,0.002124563,0.000004700367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905536,0.001789886,0.003791321,0.0001017289,0.00003414871,0.00002867867,0.0009596223,0.0002209324,0.002520128],"genre_scores_gemma":[0.9929864,0.0007491726,0.002435817,0.0000794454,0.00001313908,0.00004202932,0.00174946,0.00004088364,0.00190364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000813969,"threshold_uncertainty_score":0.002722979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286691419493592,"score_gpt":0.2119522021777075,"score_spread":0.1990852879827715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}