{"id":"W3111468108","doi":"10.1016/j.ccell.2020.11.009","title":"Immunomodulation by targeted anticancer agents","year":2020,"lang":"en","type":"review","venue":"Cancer Cell","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":216,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"High-end Foreign Experts Recruitment Plan of China; Bristol-Myers Squibb Canada; Weill Cornell Medical College; Labex Immuno-Oncology; European Research Area Network on Cardiovascular Diseases; PharmaMar; Stand Up To Cancer; Institut Universitaire de France; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Ligue Contre le Cancer; Leukemia and Lymphoma Society; Fondation pour la Recherche Médicale; AstraZeneca; Institut National Du Cancer; Bayer HealthCare; Institut National de la Santé et de la Recherche Médicale; Genentech; Institut Gustave-Roussy; Agence Nationale de la Recherche; Fondation Leducq; U.S. Department of Defense; Institut Mérieux; European Commission; Seerave Foundation; Association pour la Recherche sur le Cancer; Weill Cornell Medicine; E-Rare; Bristol-Myers Squibb; Roche; Boehringer Ingelheim","keywords":"Targeted therapy; Carcinogenesis; Cancer research; Medicine; Cancer; Pharmacology; Biology; Immunology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004449573,0.001172424,0.001319608,0.001204601,0.0001635469,0.0008578018,0.0006058626,0.000884225,0.002516131],"category_scores_gemma":[0.000492873,0.0002592744,0.0003313901,0.001166077,0.000366903,0.0007948659,0.000547021,0.001863553,0.001754656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005494399,"about_ca_system_score_gemma":0.0005222328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005577312,"about_ca_topic_score_gemma":0.001267165,"domain_scores_codex":[0.9998845,0.00002223346,0.00001227986,0.00002163462,0.00004075452,0.00001861817],"domain_scores_gemma":[0.9998775,0.00005139393,0.00002196171,0.000005438491,0.0000274474,0.00001629475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001730861,0.00009807366,0.000106051,0.008036106,0.000059056,0.0001501533,0.00002390282,0.0004880104,0.003914803,0.003059993,0.04509737,0.9387933],"study_design_scores_gemma":[0.00005042574,0.0001476607,0.0005137731,0.001381909,0.0001068858,0.0007033173,0.00002055448,0.0001782669,0.001076835,0.001244371,0.994563,0.00001309276],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001424689,0.9980217,0.0001733155,0.0001770741,0.0004094064,0.000006306571,0.00001793205,0.000009660853,0.001042018],"genre_scores_gemma":[0.001099052,0.9966288,0.0001909315,0.0003092986,0.0004692496,0.0000131156,0.0000416879,0.000002305497,0.001245555],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002516131,"threshold_uncertainty_score":0.008417249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02971145154150009,"score_gpt":0.3039444691408849,"score_spread":0.2742330175993848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}