{"id":"W3111470079","doi":"10.3390/vaccines8040773","title":"Understanding GroEL and DnaK Stress Response Proteins as Antigens for Bacterial Diseases","year":2020,"lang":"en","type":"review","venue":"Vaccines","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Government of Canada; University of Saskatchewan","keywords":"GroEL; Biology; Immune system; Heat shock protein; Antigen; Virulence; HSP60; Chaperone (clinical); Microbiology; Organism; Cell biology; Intracellular; Immunogenicity; Intracellular parasite; Bacteria; Hsp70; Immunology; Escherichia coli; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004310784,0.0007516351,0.0008988313,0.00244951,0.0002418569,0.0009301135,0.000651711,0.001131538,0.003154985],"category_scores_gemma":[0.0005931839,0.0002141202,0.000375291,0.001931493,0.0004602559,0.001547521,0.000605083,0.001624629,0.001957969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000594674,"about_ca_system_score_gemma":0.0009500454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007984822,"about_ca_topic_score_gemma":0.001140868,"domain_scores_codex":[0.9998753,0.00002054104,0.00001557735,0.00002452698,0.00004696132,0.00001697723],"domain_scores_gemma":[0.9997367,0.0001160699,0.00003358241,0.000008416807,0.00007549402,0.00002968508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000100052,0.00007837165,0.0002027402,0.02218042,0.00008563914,0.0002578574,0.00008320069,0.0003835823,0.003734206,0.007570118,0.03920063,0.9261232],"study_design_scores_gemma":[0.000009493352,0.00007740431,0.0005914285,0.002606869,0.00006826542,0.0008576873,0.00005140071,0.000075708,0.0006158138,0.002035148,0.9929978,0.00001311749],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001124372,0.9981874,0.0001251688,0.0003096316,0.0002846574,0.000003237286,0.00001303242,0.000007209127,0.0009572289],"genre_scores_gemma":[0.0005690348,0.9982503,0.0001466881,0.0001919839,0.0001920991,0.0000044323,0.00002351723,0.000001470536,0.0006204258],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003154985,"threshold_uncertainty_score":0.01055449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1100490506964368,"score_gpt":0.3703125246045856,"score_spread":0.2602634739081487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}