{"id":"W3111474440","doi":"10.3906/kim-2005-19","title":"Computational and biological studies of novel thiazolyl coumarin derivatives synthesized through Suzuki coupling","year":2020,"lang":"en","type":"article","venue":"TURKISH JOURNAL OF CHEMISTRY","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Higher Education Commission, Pakistan; University of Ottawa","keywords":"Chemistry; Thiazole; Coumarin; Aryl; Combinatorial chemistry; Trichoderma harzianum; Antimicrobial; Suzuki reaction; Yield (engineering); Antibacterial activity; Docking (animal); In vitro; Stereochemistry; Organic chemistry; Biochemistry; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002203123,0.0001866056,0.0006357242,0.000006998736,0.00006350211,0.00001933996,0.0002180007,0.0001588957,0.0002744443],"category_scores_gemma":[0.001517675,0.0001237305,0.000150713,0.00007127044,0.0004047204,0.00009260818,0.0001273178,0.0003132319,4.371073e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002705055,"about_ca_system_score_gemma":0.00004891274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001489628,"about_ca_topic_score_gemma":4.326547e-8,"domain_scores_codex":[0.9988341,0.000005784352,0.0005574029,0.0002032181,0.0002447606,0.0001547191],"domain_scores_gemma":[0.9977328,0.001226151,0.0006217716,0.00007048444,0.0002490368,0.0000997402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002975741,0.0001999711,0.006375127,0.0002551479,0.0002882969,0.00001408056,0.0002778834,0.0002278727,0.9913286,0.00002497303,0.0001065035,0.0006039605],"study_design_scores_gemma":[0.0009239374,0.00006206768,0.00158033,0.0002026041,0.00005195548,0.00009881318,0.001445171,0.0006327688,0.9939055,0.0006352876,0.0002817459,0.0001797889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961124,0.00210937,0.0003034404,0.0008380748,0.00001778008,0.00002196528,0.00003224581,0.00001717815,0.0005475644],"genre_scores_gemma":[0.9965106,0.0005625263,0.002545724,0.0001197338,0.0002377044,0.000001324565,0.000004114267,0.000007982185,0.00001027481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004794796,"threshold_uncertainty_score":0.5045583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1246860527402791,"score_gpt":0.3109392499897731,"score_spread":0.1862531972494941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}