{"id":"W3111586991","doi":"10.1002/alz.042269","title":"Biomarkers of agitation in moderate‐to‐severe Alzheimer's disease patients enrolled in an RCT with nabilone","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baycrest Hospital; Toronto Rehabilitation Institute; Sunnybrook Health Science Centre; Occupational Cancer Research Centre; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Biomarker; Internal medicine; Placebo; Medicine; Randomized controlled trial; Metabolite; Gastroenterology; Psychology; Chemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004440913,0.0009264254,0.002208203,0.0003381011,0.0004595113,0.0008896514,0.0004633503,0.0009962693,0.00135645],"category_scores_gemma":[0.005082732,0.0005225569,0.002170054,0.0004212714,0.0004997049,0.0005957386,0.000577443,0.001178988,0.0001811963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006460977,"about_ca_system_score_gemma":0.001639986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001560759,"about_ca_topic_score_gemma":0.003447467,"domain_scores_codex":[0.9969861,0.00201332,0.0003995765,0.0002432672,0.0001807551,0.0001769832],"domain_scores_gemma":[0.9966488,0.0008037862,0.00113641,0.0002753455,0.0004575656,0.0006780791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8874769,0.009338895,0.07349315,0.001518706,0.007150593,0.00006474492,0.0002782257,0.0001744748,0.00375663,0.00003743162,0.00030395,0.01640627],"study_design_scores_gemma":[0.3590994,0.2963251,0.3277865,0.0002790663,0.01205509,0.00009657429,0.000257871,0.0008421268,0.001615828,0.0001751621,0.001398838,0.00006836548],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958351,0.002650778,0.0001389547,0.00009136795,0.00008609065,0.0008202748,0.0001345867,0.000008668352,0.0002342692],"genre_scores_gemma":[0.9977794,0.0004734175,0.0003446721,0.0001314815,0.0000615016,0.0008521912,0.0001576807,0.00000143367,0.0001982709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004440913,"threshold_uncertainty_score":0.02348608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03266657739623738,"score_gpt":0.2622811115434648,"score_spread":0.2296145341472275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}