{"id":"W3111710464","doi":"10.1093/neuonc/noaa222.259","title":"GCT-41. RESPONSE-BASED RADIATION THERAPY IN PATIENTS WITH NEWLY DIAGNOSED CENTRAL NERVOUS SYSTEM LOCALIZED GERMINOMA: A CHILDREN’S ONCOLOGY GROUP (COG) PROSPECTIVE PHASE 2 CLINICAL TRIAL","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Cog; Carboplatin; Etoposide; Germinoma; Chemotherapy; Radiation therapy; Phases of clinical research; Internal medicine; Central nervous system; Surgery; Oncology; Gastroenterology; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00184584,0.0009986536,0.00137697,0.0002879894,0.0003482937,0.000945578,0.000629545,0.0009900829,0.002395125],"category_scores_gemma":[0.0005617391,0.0003511564,0.001129234,0.0004104428,0.0007483028,0.0004613903,0.0003253598,0.001873652,0.0004509438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008647137,"about_ca_system_score_gemma":0.001800659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001484207,"about_ca_topic_score_gemma":0.004016919,"domain_scores_codex":[0.9996062,0.000203816,0.00001927154,0.00006579333,0.00003723106,0.00006779533],"domain_scores_gemma":[0.999558,0.00006027033,0.00008225557,0.00003908028,0.00002575186,0.0002346188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8609983,0.0369372,0.02272393,0.000787117,0.001367239,0.0002661986,0.0002089567,0.002265098,0.01063435,0.0002375554,0.003442616,0.06013136],"study_design_scores_gemma":[0.6313123,0.3251597,0.03625116,0.00005440725,0.0007049459,0.0002965976,0.00006696522,0.001284053,0.00162083,0.0001932001,0.003025329,0.00003046288],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995683,0.00142378,0.0001062667,0.0002639614,0.00007300219,0.001062589,0.0006215841,0.000036229,0.0007296005],"genre_scores_gemma":[0.9919325,0.001430712,0.0006888461,0.0007065562,0.0001539971,0.001596068,0.001989698,0.00001422303,0.001487561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002395125,"threshold_uncertainty_score":0.00976181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02977931541336713,"score_gpt":0.3299005253535205,"score_spread":0.3001212099401533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}