{"id":"W3111755010","doi":"10.1093/neuonc/noaa222.036","title":"DDEL-01. ENHANCING DRUG DELIVERY WITH MRgFUS FOR DIFFUSE INTRINSIC PONTINE GLIOMA MODEL","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Hospital for Sick Children","funders":"","keywords":"Medicine; Doxorubicin; Brainstem; In vivo; Glioma; Microbubbles; Drug; Blood–brain barrier; Pharmacology; Pathology; Cancer research; Chemotherapy; Central nervous system; Internal medicine; Ultrasound; Biology; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904035,0.000376711,0.0002821298,0.0003233896,0.0001280292,0.0001724951,0.0002722353,0.0004055154,0.001358595],"category_scores_gemma":[0.0000867052,0.0001175454,0.0002061571,0.0002220665,0.0002832451,0.000235409,0.0001333628,0.0006756156,0.0003737641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003515728,"about_ca_system_score_gemma":0.0003301209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00164373,"about_ca_topic_score_gemma":0.002092038,"domain_scores_codex":[0.9998742,0.00001447464,0.000007811971,0.00003283992,0.0000370239,0.00003349778],"domain_scores_gemma":[0.9999222,0.0000111649,0.0000191421,0.000008746974,0.00001051179,0.0000282268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002321043,0.0001443928,0.00009676035,0.00006740848,0.000005309202,0.00008683895,0.00002209976,0.0001036326,0.9966502,0.000123641,0.0001560435,0.002311456],"study_design_scores_gemma":[0.00004533155,0.001669461,0.0008602495,0.000003887908,0.00001599238,0.0002313213,0.00001495192,0.0007821837,0.9940132,0.00002394635,0.00233548,0.000003932526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901677,0.001468689,0.005280831,0.0002209684,0.00005605501,0.0001394739,0.0007130206,0.0002310476,0.001722118],"genre_scores_gemma":[0.9843833,0.001469676,0.007448382,0.00009072523,0.00001197698,0.0002081681,0.001074931,0.00003724642,0.005275588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00164373,"threshold_uncertainty_score":0.004544973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172740391195381,"score_gpt":0.2687987008879853,"score_spread":0.2470712969760315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}