{"id":"W311177223","doi":"10.1371/journal.pone.0124960","title":"Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Defense","keywords":"Hepatocyte growth factor; Receptor tyrosine kinase; RHOA; ABL; Cell biology; Kinase; Cancer research; Tyrosine kinase; Biology; Hepatocyte Growth Factor Receptor; Receptor Protein-Tyrosine Kinases; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Receptor; C-Met; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003856285,0.0002133535,0.0004888076,0.00007741825,0.00006176021,0.00002174746,0.00008180238,0.0001069452,0.00005037953],"category_scores_gemma":[0.0003026383,0.0001960082,0.0000670088,0.00009882745,0.00009303903,0.00008629645,0.00007636497,0.00007626312,0.00003756689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005478087,"about_ca_system_score_gemma":0.0002985925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001470061,"about_ca_topic_score_gemma":0.000009345765,"domain_scores_codex":[0.9984934,0.00004912722,0.00029841,0.0004241046,0.0003877706,0.0003471666],"domain_scores_gemma":[0.9987826,0.000100624,0.000103408,0.0004289488,0.0002204035,0.0003640496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001222368,0.002269736,0.03186481,0.001133227,0.0006672642,0.00006941333,0.0007344059,0.00001881673,0.9589121,0.000008294917,0.0006851458,0.002414406],"study_design_scores_gemma":[0.01113045,0.001429911,0.006219353,0.0004570291,0.001429881,0.00002241281,0.0001362149,0.001203531,0.9768295,0.0004889475,0.0004024218,0.0002503932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970083,0.001134421,0.00005523161,0.0003264286,0.00005610239,0.0008755028,0.00009824619,0.0001061203,0.0003396606],"genre_scores_gemma":[0.9827384,0.00004186202,0.0148264,0.0001320436,0.0002945413,0.00009625882,0.00008850406,0.00004952163,0.001732487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02564545,"threshold_uncertainty_score":0.7992981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08990283362504954,"score_gpt":0.2675006078183309,"score_spread":0.1775977741932814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}