{"id":"W3111796351","doi":"10.1093/neuonc/noaa222.501","title":"MBCL-25. PILOT STUDY OF A SURGERY AND CHEMOTHERAPY-ONLY APPROACH IN THE UPFRONT THERAPY OF CHILDREN WITH WNT-POSITIVE STANDARD RISK MEDULLOBLASTOMA: UPDATED OUTCOMES","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Medulloblastoma; Chemotherapy; Regimen; Vincristine; Radiation therapy; Chemotherapy regimen; Surgery; Cyclophosphamide; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001194976,0.0005041021,0.0009241091,0.0003700776,0.0003048248,0.0005300122,0.0005874321,0.0004463854,0.001370513],"category_scores_gemma":[0.0006972526,0.0001933189,0.0006760912,0.0003037728,0.0004431798,0.0003753137,0.0003024407,0.0007443562,0.0003257425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009368163,"about_ca_system_score_gemma":0.001466965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005712341,"about_ca_topic_score_gemma":0.01183913,"domain_scores_codex":[0.9995389,0.0002117802,0.0000337093,0.0000687936,0.00005829279,0.00008854442],"domain_scores_gemma":[0.9994479,0.00009774666,0.0001176195,0.00003996702,0.00004151797,0.0002552999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3484623,0.09234543,0.1711648,0.000937889,0.001725596,0.001951079,0.0008897179,0.002862487,0.03568802,0.000301022,0.003277904,0.3403937],"study_design_scores_gemma":[0.05464312,0.7517865,0.1794634,0.00009296496,0.001075556,0.0009584425,0.0002918617,0.001050164,0.006186854,0.00007585256,0.004343949,0.00003134695],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972081,0.001070576,0.0001197647,0.00008082716,0.00001307675,0.0004452217,0.0004424317,0.0000222497,0.0005978242],"genre_scores_gemma":[0.9957495,0.001060199,0.0007418777,0.0001533571,0.0000361718,0.0004453243,0.001179353,0.000009069025,0.0006250723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005712341,"threshold_uncertainty_score":0.01135814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02881990244726914,"score_gpt":0.2799672016497182,"score_spread":0.2511472992024491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}