{"id":"W3111796351","doi":"10.1093/neuonc/noaa222.501","title":"MBCL-25. PILOT STUDY OF A SURGERY AND CHEMOTHERAPY-ONLY APPROACH IN THE UPFRONT THERAPY OF CHILDREN WITH WNT-POSITIVE STANDARD RISK MEDULLOBLASTOMA: UPDATED OUTCOMES","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Medulloblastoma; Chemotherapy; Regimen; Vincristine; Radiation therapy; Chemotherapy regimen; Surgery; Cyclophosphamide; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003195094,0.0002484784,0.00105059,0.0001302196,0.00004578969,0.000007752001,0.0001200435,0.00006288998,0.00001952522],"category_scores_gemma":[0.00006340084,0.0001367563,0.00007246734,0.0003507582,0.0001668616,0.00003738124,0.00003600765,0.0002555485,7.48112e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005246713,"about_ca_system_score_gemma":0.0001937948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003117805,"about_ca_topic_score_gemma":0.0001524023,"domain_scores_codex":[0.9980373,0.0005461302,0.0004505439,0.0003980566,0.0003421292,0.0002258154],"domain_scores_gemma":[0.9985586,0.0006460207,0.0003353562,0.0002676188,0.00009491125,0.00009743382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005043543,0.008261011,0.9674297,0.00001171425,0.0007787737,0.0001117364,0.005481376,0.00001150665,0.002162718,0.0000138402,0.0004274503,0.01026662],"study_design_scores_gemma":[0.01586358,0.03763857,0.9409766,0.0000125143,0.0002149491,0.00009590133,0.001850644,0.00002150799,0.003063031,0.000004702338,0.0001546903,0.0001033699],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993888,0.0002859194,0.000009815253,0.003535667,0.00002775537,0.002007996,0.00005494775,0.00002267016,0.0001672158],"genre_scores_gemma":[0.9976532,0.000343687,0.0001022554,0.001713221,0.00002790772,0.0001038053,0.0000249169,0.00003047794,4.916092e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02937756,"threshold_uncertainty_score":0.5576761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02881990244726914,"score_gpt":0.2799672016497182,"score_spread":0.2511472992024491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}