{"id":"W3111829628","doi":"10.1093/neuonc/noaa215.281","title":"EPCO-02. MOLECULAR CHARACTERIZATION OF TWO NOVEL MPNST SUBGROUPS IDENTIFIES THERAPEUTIC OPPORTUNITIES","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Cancer research; Wnt signaling pathway; Biology; Targeted therapy; Transcriptome; Medicine; Internal medicine; Signal transduction; Cancer; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002849729,0.0002369572,0.0002729456,0.0005564619,0.0003112143,0.0006055053,0.000300877,0.000457638,0.003170665],"category_scores_gemma":[0.0004324068,0.0001249246,0.0002049619,0.0004153308,0.0001893135,0.0002449541,0.0003113882,0.000581028,0.0009583246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004429893,"about_ca_system_score_gemma":0.0004326917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009768552,"about_ca_topic_score_gemma":0.001461221,"domain_scores_codex":[0.9998307,0.00001518016,0.00001064768,0.00005816285,0.00004729527,0.00003799832],"domain_scores_gemma":[0.9997053,0.00003900773,0.00005310933,0.00003280679,0.00006997507,0.00009975384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002998491,0.0002539791,0.1073573,0.0002734408,0.00009058527,0.0006456263,0.0001388776,0.000758776,0.8275714,0.0006795533,0.003714586,0.0555174],"study_design_scores_gemma":[0.0002656591,0.001652671,0.6006203,0.0000756155,0.0002339369,0.005013964,0.0003729319,0.009032816,0.3431528,0.001196332,0.03834913,0.00003385239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868698,0.001138127,0.002171712,0.0002742865,0.00003275114,0.000150664,0.004979313,0.0001417656,0.004241657],"genre_scores_gemma":[0.9790087,0.0004099251,0.003391465,0.000239218,0.00002053864,0.0001798709,0.01328113,0.00006606285,0.003403051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003170665,"threshold_uncertainty_score":0.01060694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07732098688833675,"score_gpt":0.3078528578268717,"score_spread":0.2305318709385349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}